Evidence map›Paper›PMID 42174292›Full record

ArticleArchives of virology2026

First molecular and phylogenetic study of the bovine lumpy skin disease virus declared in Algeria in 2024.

Abdelheq Barberis, Noureddine Tabet, Ourida Rahal, Imen Larbi, Ryme Amira Zerdoumi, Ali Boumegoura, Ryme Agred, Merièm Khoualed, Jihene Lachheb

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Article in Archives of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Abdelheq BarberisBiotechnology and Health Division, Biotechnology Research Center, Mendjli Nouvelle Ville UV 03 BP E73, Constantine, 25016, Algeria. abdelheqbarberis5@gmail.com.ORCID http://orcid.org/0000-0001-6854-2752
Noureddine TabetEpidemiological Surveillance Laboratory, Health, Production and Reproduction, Experimentation and Cell Therapy of Domestic and Wild Animals, Agricultural Sciences Department, Chadli Bendjedid University, B.P 73, El-Tarf, 36000, Algeria.
Ourida RahalBiotechnology and Health Division, Biotechnology Research Center, Mendjli Nouvelle Ville UV 03 BP E73, Constantine, 25016, Algeria.
Imen LarbiLaboratory of Epidemiology and Veterinary Microbiology, Institut Pasteur de Tunis, University of Tunis El Manar, 13, Place Pasteur- BP74, Tunis, Belvédère, LR19IPT03, 1002, Tunisia.
Ryme Amira ZerdoumiDepartment of Biology, Faculty of Natural and Life Sciences, University of Constantine 2, Constantine, 25000, Algeria.
Ali BoumegouraBiotechnology and Health Division, Biotechnology Research Center, Mendjli Nouvelle Ville UV 03 BP E73, Constantine, 25016, Algeria.
Ryme AgredBiotechnology and Health Division, Biotechnology Research Center, Mendjli Nouvelle Ville UV 03 BP E73, Constantine, 25016, Algeria.
Merièm KhoualedBiotechnology and Health Division, Biotechnology Research Center, Mendjli Nouvelle Ville UV 03 BP E73, Constantine, 25016, Algeria.
Jihene LachhebLaboratory of Epidemiology and Veterinary Microbiology, Institut Pasteur de Tunis, University of Tunis El Manar, 13, Place Pasteur- BP74, Tunis, Belvédère, LR19IPT03, 1002, Tunisia. jihene.lachheb@pasteur.tn.ORCID http://orcid.org/0000-0001-8043-3903

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lumpy skin disease (LSD) is a re-emerging transboundary viral disease of major economic importance affecting cattle worldwide. In Algeria, LSD was reported for the first time in June 2024, based on clinical observations and serological evidence. This study aimed to perform molecular detection and phylogenetic characterization of the first LSD virus (LSDV) strains circulating in Algeria. From June to August 2024, blood samples were collected from clinically affected cattle in eastern Algeria, a region characterized by active outbreaks and environmental conditions favorable to vector-borne transmission. Animals exhibited typical clinical signs of LSD, including fever, generalized skin nodules, ocular and nasal discharge, and lymphadenopathy. Blood samples were selected to detect LSDV during the viremic phase of infection and enable molecular confirmation under field conditions. Molecular detection was performed using PCR targeting the P32 gene for specific identification of Capripoxvirus. Selected samples were further analyzed using a multi-target PCR approach targeting partial P32 and F genes, as well as complete GPCR and RPO30 genes, followed by sequencing and phylogenetic analysis. LSDV was successfully detected, and sequence analysis revealed genetically homogeneous strains belonging to the pathogenic clade. The Algerian isolates showed close genetic relationships with strains circulating across Africa, the Middle East, Asia, and Europe, suggesting a shared epidemiological origin. A characteristic deletion in the GPCR gene further distinguished field strains from vaccine-related strains. This study provides the first molecular and phylogenetic characterization of LSDV associated with the initial outbreak in Algeria, highlighting transboundary spread patterns and emphasizing the need for enhanced surveillance to monitor virus circulation and evolution and evolution.

Indexed as

Lumpy Skin DiseaseLumpy skin disease virusPhylogenyAlgeriaAnimalsCattle

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.