ArticleCommunications medicine2026
Genomic evolution and climate related drivers of cholera surges in Dhaka Bangladesh between 1996 and 2024.
Article in Communications medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Climate factors and evolution drive cholera surges in Dhaka.Nature reviews. Microbiology · 2026Article
- Genomic evolution and climate related drivers of cholera surges in Dhaka Bangladesh between 1996 and 2024.Communications medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
Abstract
backgroundCholera, a climate-associated diarrhea occurs endemically in Dhaka city, Bangladesh, often turning into large epidemics. In 2022, a massive outbreak struck Dhaka city, resulting in a very high number of cholera cases. Although extensive studies have focused on climate and cholera, including genomic evolution of the causative agent, Vibrio cholerae, their association with the case surges remains poorly understood.
methodsWe analyzed cholera data between 1996 and 2024 from the Diarrheal Disease Surveillance System (DDSS) of icddr,b, and also conducted a follow up genomic analysis of V. cholerae O1 El Tor by including newly sequenced and archived sequence data. Integrated analyses of genomic, climatic, and cholera surveillance data investigated the role of different factors on yearly case surges in Dhaka city.
resultsAnalysis of DDSS data shows temporal changes of cholera cases across Dhaka city, and genomic analysis shows continuous evolution of V. cholerae. Association analysis of cholera case data against the genomic data reveals that co-circulation of multiple lineages/sub lineages of V. cholerae, as well as their flux between the years with newly introduced or re-emerged lineages, are significantly (p-value <= 0.05) associated with the yearly cholera cases in Dhaka city. Integrated statistical association analysis of cholera cases with the climate and genomic evolutionary factors also reveals a significant association.
conclusionsThis study associates climate factors and the V. cholerae genome evolutionary events with interannual variation, such as high and low cholera, including surges of the disease in Dhaka city.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.