Trial reportScientific reports2026
Randomized controlled trial of PERMA-based intervention on subjective well-being and post-traumatic growth in young and middle-aged stroke survivors during rehabilitation.
Trial report in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
10 authors.
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Abstract
Young and middle-aged stroke patients face unique rehabilitation-related psychological distress-such as frustration from slow motor function recovery, anxiety about losing family/social roles, and low motivation for long-term rehabilitation-all of which directly hinder physical recovery and post-stroke adaptation. This study developed a rehabilitation-aligned PERMA (positive emotions, engagement, relationships, meaning, achievement) intervention-rooted in positive psychology and tailored to stroke-specific needs-and evaluated its efficacy in improving subjective well-being (SWB) and post-traumatic growth (PTG) in young and middle-aged stroke patients. A total of 132 eligible patients were randomized into two groups (66 per group) via 1:1 simple randomization, using a computer-generated random number table with allocation concealment via sealed envelopes. The control group received conventional rehabilitation, while the intervention group supplemented with 8 structured PERMA-based sessions over 4 weeks. SWB and PTG were assessed at baseline, post-intervention, 1-month, and 3-month follow-ups. Statistical analyses included independent samples t-tests (between-group comparisons) and repeated-measures ANOVAs (longitudinal changes). SWB scores were significantly higher in the intervention group than in the control group at post-intervention, 1-month, and 3-month follow-ups (t = 2.584, 5.572, 6.099; P < 0.05); PTG scores were also significantly higher at these time points (t = 2.750, 3.948, 5.300; P < 0.01). Repeated-measures ANOVAs confirmed statistically significant time-dependent increases in both outcomes for the intervention group (P < 0.01), with no such significant trend in the control group. The rehabilitation-aligned PERMA intervention effectively enhances SWB and PTG in young and middle-aged stroke patients during recovery. By integrating positive psychology with functional rehabilitation goals, it addresses the unique psychological needs of this population and provides a feasible, clinically applicable support strategy that complements physical rehabilitation.Trial Registration: Registration number of China Clinical Trials Registration Center: ChiCTR2200060103, First Posted date: 18/05/2022, Date of first participant enrollment: 01/12/2022.
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