Evidence map›Paper›PMID 42174086›Full record

ArticleScientific reports2026

Emergence of NDM-5-producing ST405 and NDM-1-producing ST10 Escherichia coli in bloodstream infections in Apulia, Italy, 2023-2025.

Anna Sallustio, Marisa Accogli, Davide Sacco, Marilina Santantonio, Vito Colella, Domenica Maria Di Palo, Serafina Rutigliano, Grazia Punzi, Francesca Centrone, Maria Chironna

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anna Sallustio *Laboratory of Public Health Unit, Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari, Bari, Italy.
Marisa Accogli *Laboratory of Public Health Unit, Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari, Bari, Italy.
Davide SaccoDepartment of Interdisciplinary Medicine, Hygiene Section, University of Bari Aldo Moro, Bari, Italy.
Marilina SantantonioLaboratory of Public Health Unit, Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari, Bari, Italy.
Vito ColellaDepartment of Interdisciplinary Medicine, Hygiene Section, University of Bari Aldo Moro, Bari, Italy.
Domenica Maria Di PaloLaboratory of Public Health Unit, Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari, Bari, Italy.
Serafina RutiglianoLaboratory of Public Health Unit, Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari, Bari, Italy.
Grazia PunziLaboratory of Public Health Unit, Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari, Bari, Italy.
Francesca CentroneLaboratory of Public Health Unit, Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari, Bari, Italy.
Maria ChironnaLaboratory of Public Health Unit, Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari, Bari, Italy. maria.chironna@uniba.it.

Funding

NextGenerationEU PE00000007, INF-ACT
6 · The paper itself

Abstract

NDM-producing Escherichia coli (E. coli) are emerging across Europe, especially clones ST405 (NDM-5) and ST10 (NDM-1). Data from Southern Italy remain scarce. We investigated NDM-producing E. coli bloodstream infections (BSIs) detected through regional Carbapenem-resistant Enterobacteriaceae (CRE) surveillance in Apulia, 2014-2025. Within the regional CRE surveillance (2014-2025), all carbapenem-resistant (CR) E. coli BSI isolates were collected and screened for carbapenemase genes (GeneXpert: blaKPC, blaVIM, blaNDM, blaIMP, blaOXA-48). NDM-positive isolates (2023-2025) underwent Illumina whole-genome sequencing (WGS). Core-genome SNP analysis assessed clonal relatedness. Resistance, virulence genes, and plasmid replicons were characterized using ResFinder, VirulenceFinder, and PlasmidFinder, respectively. Among 50 CR E. coli BSI isolates, bla

Indexed as

Bacteremiabeta-LactamasesEscherichia coliEscherichia coli InfectionsEscherichia coli ProteinsAnti-Bacterial AgentsDrug Resistance, Multiple, BacterialHumansItalyMicrobial Sensitivity TestsPlasmidsWhole Genome SequencingAnti-Bacterial Agentsbeta lactamase NDM-5, E colibeta-LactamasesEscherichia coli ProteinsNDM-1 protein, E coliBloodstream infectionsEscherichia coliNDM-5ST405Whole-genome sequencing

Identifiers

PMID42174086
PMCPMC13415540

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.