Evidence map›Paper›PMID 42174056›Full record

Trial reportScientific reports2026

Effect of pearl millet diet on immunomodulating factors, physical performance and recovery in athletes: a randomised control trial.

Alisha Saifi, Kommi Kalpana, Gulshan Lal Khanna, Dayakar Rao Benhur, Gurseen Rakhra, Ekta Tanwar

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alisha SaifiDepartment of Nutrition and Dietetics, School of Allied Health Sciences, Manav Rachna International Institute of Research & Studies, Faridabad, 121004, Haryana, India.
Kommi KalpanaDepartment of Nutrition and Dietetics, School of Allied Health Sciences, Manav Rachna International Institute of Research & Studies, Faridabad, 121004, Haryana, India. kommikalpana80@gmail.com.
Gulshan Lal KhannaShree Guru Gobind Singh Tricentenary University, Gurugram, 122505, Haryana, India.
Dayakar Rao BenhurICAR - Indian Institute of Millets Research, Hyderabad, India.
Gurseen RakhraDepartment of Nutrition and Dietetics, School of Allied Health Sciences, Manav Rachna International Institute of Research & Studies, Faridabad, 121004, Haryana, India.
Ekta TanwarDepartment of Nutrition and Dietetics, School of Allied Health Sciences, Manav Rachna International Institute of Research & Studies, Faridabad, 121004, Haryana, India.

Funding

National Food Security Mission (NFSM), Indian Council of Agricultural Research (ICAR), Ministry of Agriculture and Farmers Welfare (MOAFM), Government of India F.No.18-3/2022-NFSM (FTS-111308E)
6 · The paper itself

Abstract

A pearlmilletbased diet may help modulate inflammatory cytokines and support better recovery in athletes exposed to high training stress. Its rich profile of fiber, minerals, and antioxidants suggests potential benefits for reducing inflammation and enhancing physical performance. However, evidence in athletic populations remains limited, prompting investigation into its functional impact. To explore the effect of pearl millet diet on immunomodulating factors, physical performance and recovery in athletes. A randomised controlled trial was conducted among male athletes aged 18-25 years (n = 60), who were randomly allocated into an experimental group (EG; n = 28) and a control group (CG; n = 30). The EG received a pearl millet-based diet (1/3 substitution of regular cereals with pearl millet) for 60 days, while the CG continued with their habitual cereal diet. Pre- and post-intervention assessments included body composition, immunomodulatory markers (IL-6, TNF-α, Hs-CRP), and measures of physical performance and recovery.Between-group differences at post-intervention were analysed using analysis of covariance (ANCOVA), adjusting for baseline values. Within-group changes were assessed using paired sample t-tests. Statistical significance was set at p < 0.05. The experimental group showed a significant increase in muscular strength (kg) from 35.3 ± 7.59 to 42.8 ± 9.14. VO₂ max (mL·kg⁻¹·min⁻¹) increased from 47.8 ± 4.76 to 49.5 ± 4.79, while resting heart rate (beats/min) decreased from 80 ± 10.56 to 75 ± 11.16. Additionally, cumulative time (min) increased from 10.7 ± 4.12 to 12.8 ± 4.51, and distance covered in the endurance test (m) improved from 1359.0 ± 556.74 to 1565.7 ± 571.20.No significant changes were observed in serum Hs-CRP (mg/L), TNF-α (pg/mL), or IL-6 (pg/mL) levels in the EG. A 60-day pearl millet dietary intervention may enhance strength and endurance performance in the EG. However, it did not appear to produce notable changes in most immunomodulatory markers or recovery indicators.

Indexed as

AthletesAthletic PerformanceDietPennisetumAdolescentAdultBody CompositionHumansInterleukin-6MalePost-Exercise RecoveryTumor Necrosis Factor-alphaYoung AdultInterleukin-6Tumor Necrosis Factor-alphaAthletesBody compositionImmunityPearl milletPhysical performance

Identifiers

PMID42174056
PMCPMC13443783

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.