Observational studyScientific reports2026
Clinical outcomes associated with Korean medicine home-visit care for patients with cognitive impairment: a multi-center retrospective observational study.
Observational study in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
This multi-center retrospective study investigated associations between a 4-month Korean medicine (KM) home-visit program and pain, behavioral and psychological symptoms of dementia (BPSD), cognitive function, and caregiver burden in 92 patients with cognitive impairment (Global Deterioration Scale stages 2-5) assessed at baseline, 2 months, and 4 months. Complete case analysis was the primary analytical approach. Significant improvements were observed in Pain Assessment in Advanced Dementia: median 4 to 2, p < 0.001) and neuropsychiatric symptom severity (Neuropsychiatric Inventory Questionnaire: 3 to 2, p = 0.006). While Mini-Mental State Examination for Dementia Screening remained stable; the Clock Drawing Test showed a non-significant trend toward improvement (p = 0.098). Caregiver burden (12-item Zarit Burden Interview [ZBI-12]) showed a non-significant trend toward reduction (p = 0.074). Subgroup analyses showed exploratory within-group signals for ZBI-12 (mild cognitive impairment group) and CDT (dementia group); between-group differences were not significant. Improvements in BPSD severity strongly correlated with reduced caregiver distress (rho = 0.721, p < 0.001). A 4-month KM home-visit program was associated with significant reductions in pain and BPSD, with stable cognitive outcomes. These hypothesis-generating findings support integrating KM services into community-based dementia care and the design of future controlled trials.
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