ArticleCommunications biology2026
Non-calyceal inputs gate the timing of calyx of Held evoked MNTB output.
Article in Communications biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Development of Calcium Signaling in Postsynaptic Neurons of the Medial Nucleus of the Trapezoid Body in the Mouse.Journal of the Association for Research in Otolaryngology : JARO · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Synaptic filtering by short-term plasticity (STP) influences the strength and timing of the input-output function of neurons during ongoing activity. In the medial nucleus of the trapezoid body (MNTB), an ultrafast sign-inverting relay, short-term depression (STD) of the dominant calyx of Held inputs affects the exquisite output timing of these neurons and thereby influences sound processing relevant for sound source localization. We find that additional excitatory non-calyceal inputs, targeting soma and dendrites of MNTB neurons, show prominent frequency-dependent facilitation and asynchronous release leading to a steady depolarizing conductance. The integration of non-calyceal and the calyx of Held input provides a mechanism for adjusting the temporal precision and faithfulness of output during prolonged high-frequency activity in a range relevant for auditory processing. Thus, non-calyceal inputs tune suprathreshold output generation in a functionally relevant manner, qualified to set the neuronal representation of sound sources in space.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.