ArticleScientific reports2026
Categorizing health beliefs among cancer survivors using latent profile analysis to identify targets for promoting medication adherence and quality of life.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Nearly half of cancer survivors are nonadherent to oral anticancer medications (OAM), yet no studies have systematically examined health belief profiles or identified belief-based intervention targets to improve adherence and health-related quality of life (HRQoL). This study aimed to categorize distinct health belief profiles and examine their associations with medication adherence and HRQoL among cancer survivors. This cross-sectional online survey study recruited participants from two crowdsourcing panels across the U.S. between June and July 2024. Latent profile analysis was used to categorize participants' patterns of health beliefs. Eligibilities were self-reported who had a cancer diagnosis and were currently taking at least one OAM. Participants completed a 54-item online survey assessing cancer perceptions, beliefs about OAMs, medication adherence and HRQoL. One-way analysis of variance (ANOVA) and multivariate regression analysis were conducted to compare group differences and examine the associations between health belief profiles, adherence and HRQoL. Among 323 respondents, three distinct health belief profiles emerged, significantly associated with adherence (adjusted R
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