Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Neurorehabilitation and Restorative Neuroscience NetworkK12HD093427 · NICHD · GEORGETOWN UNIVERSITY · PI BREGMAN, BARBARA S, DROMERICK, ALEXANDER W · 2017 to 2021
$3.9M
Transcriptional Regulation Over Neurogenesis of Cortical Output Neuron Segmental Identity and DiversityR01NS131662 · NINDS · WINIFRED MASTERSON BURKE MED RES INST · PI Vibhu Vinodchandra Sahni · 2023 to 2026
$2.1M
Zeiss Lightsheet 7 microscopeS10OD030383 · OD · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI WANG, EXING · 2021 to 2021
$559k
An advanced, high-throughput imaging system for the BNI Structural and Functional Imaging CoreS10OD036432 · OD · WINIFRED MASTERSON BURKE MED RES INST · PI HOLLIS, EDMUND R · 2024 to 2024
$273k
Craig H. Neilsen Foundation (Neilsen Foundation) 727694New York State Department of Health - Wadsworth Center (Department of Health, Wadsworth Center) C39069GGNICHD NIH HHS K12 HD093427NIH HHS S10 OD030383NIH HHS S10 OD036432NINDS NIH HHS R01 NS131662Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) P2EZP3_191858U.S. Department of Health & Human Services | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) K12HD093427U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R01NS131662U.S. Department of Health & Human Services | NIH | NIH Office of the Director (OD) S10OD030383U.S. Department of Health & Human Services | NIH | NIH Office of the Director (OD) S10OD036432
6 · The paper itself
Abstract
Skilled movement relies on descending cortical projections to the brainstem and spinal cord. The brainstem integrates cortical inputs from subcerebral projection neurons (SCPN). Here, we identify a previously unrecognized direct cortico-brainstem circuit that emerges early in development and persists into adulthood. A subset of SCPN project exclusively to the brainstem from the earliest stages of axon extension, never extending to the spinal cord. We find that during development, these cortico-brainstem neurons (CBN) can be prospectively identified by Neuropeptide Y (Npy) expression. In adulthood, Npy
Indexed as
Brain StemCerebral CortexForelimbMotor CortexAnimalsFemaleMaleMiceMovementNeural PathwaysNeuronsNeuropeptide YSpinal CordNeuropeptide Y
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Developmental molecular signatures define de novo cortico-brainstem circuit for skilled forelimb movement. · full record | OpenQuestion