Multiple ShKT domain-containing MUL-1 proteins act as redox-responsive modulators of oxidative stress signaling in C. elegans.

Emilio Carranza-García, Abe Gayle Santos, Kyoung-Hye Yoon, Anton Gartner

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Article in Molecules and cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Emilio Carranza-GarcíaCenter for Genomic Integrity, Institute for Basic Science, UNIST-gil 50, Ulsan 44919, Republic of Korea.

Abe Gayle SantosDepartment of Physiology, Yonsei University Wonju College of Medicine, 20 Ilsan-ro, Wonju, South Korea; Organelle Medicine Research Center, Yonsei University Wonju College of Medicine, 20 Ilsan-ro, Wonju, South Korea; Department of Global Medical Science, Yonsei University Wonju College of Medicine, 20 Ilsan-ro, Wonju, South Korea.

Kyoung-Hye YoonOrganelle Medicine Research Center, Yonsei University Wonju College of Medicine, 20 Ilsan-ro, Wonju, South Korea; Department of Global Medical Science, Yonsei University Wonju College of Medicine, 20 Ilsan-ro, Wonju, South Korea.

Anton GartnerCenter for Genomic Integrity, Institute for Basic Science, UNIST-gil 50, Ulsan 44919, Republic of Korea; Department for Health Science and Technology, Ulsan National Institute of Science and Technology (UNIST), UNIST-gil 50, Ulsan 44919, Republic of Korea. Electronic address: tgartner67@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Organismal survival depends on coordinated responses to oxidative stress and DNA damage. Using Caenorhabditis elegans, we investigate mul-1, a robust transcriptional target of ionizing radiation and reactive oxygen species. Although annotated as a mucin, MUcin-Like 1 protein (MUL-1) is a small Stichodactyla helianthus K

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsOxidative StressAnimalsApoptosisHydrogen PeroxideOxidation-ReductionReactive Oxygen SpeciesSignal TransductionTranscription FactorsTumor Suppressor Protein p53Caenorhabditis elegans ProteinsCEP-1 protein, C elegansHydrogen PeroxideReactive Oxygen SpeciesTranscription FactorsTumor Suppressor Protein p53C. elegansIonizing irradiationMUL-1Oxidative stressShKT domainStress signaling

Identifiers

PMID42173292

DOI10.1016/j.mocell.2026.100376

PMCPMC13273113

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.