Evidence map›Paper›PMID 42173098›Full record

ArticleCell reports. Medicine2026

An international multidisciplinary consensus statement on laparoscopic liver biopsy.

Si-Yi Lei, Yu Han, Don C Rockey, Khalid Alswat, Vincent Wai-Sun Wong, Nozim Jumaev, Carlos Jesus Toro-Huamanchumo, Safwan Taha, Mohamed El-Kassas, Jacob George and 39 more

Abstract readConsensus Statement
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell reports. Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Liver Biopsy in Metabolic Dysfunction-Associated Steatohepatitis Clinical Trials: Potential Pitfalls and Solutions.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

49 authors.

Si-Yi LeiMAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China; Cixi Biomedical Research Institute, Wenzhou Medical University, Wenzhou, China.
Yu HanDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Don C RockeyThe Digestive Disease Research Center, Medical University of South Carolina, Charleston, SC, USA.
Khalid AlswatLiver Disease Research Center, Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Vincent Wai-Sun WongMedical Data Analytics Centre, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China; State Key Laboratory of Digestive Disease, Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, China.
Nozim JumaevDepartment of Surgical Diseases, Tashkent State Medical University, Tashkent, Almazar, Uzbekistan.
Carlos Jesus Toro-HuamanchumoOBEMET Center for Obesity and Metabolic Health, Lima, Peru; Universidad San Ignacio de Loyola, Lima, Peru; Nutrition & Health Innovation Research Institute, Edith Cowan University, Perth, WS, Australia.
Safwan TahaThe Metabolic and Bariatric Surgery Center of Excellence (SRC), Mediclinic Airport Road Hospital, Abu Dhabi, UAE.
Mohamed El-KassasEndemic Medicine Department, Faculty of Medicine, Helwan University, Cairo, Egypt; Applied Science Research Center, Applied Science Private University, Amman, Jordan; Steatotic Liver Disease Study Foundation in Middle East and North Africa (SLMENA), Cairo, Egypt.
Jacob GeorgeStorr Liver Centre, Westmead Institute for Medical Research, Westmead Hospital, University of Sydney, Sydney, NSW, Australia.
Mark MuthiahDivision of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore, Singapore; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Omar GhanemDepartment of Surgery, Mayo Clinic, Rochester, MN, USA.
Masato YonedaDepartment of Gastroenterology and Hepatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Dao Viet HangInternal Medicine Faculty, Hanoi Medical University, Hanoi, Vietnam.
Giada SebastianiDivision of Gastroenterology & Hepatology, McGill University Health Centre, Montreal, QC, Canada.
George Papatheodoridis1st Department of Gastroenterology, Medical School of National and Kapodistrian University of Athens, General Hospital of Athens "Laiko", Athens, Greece.
Adam Abu-AbeidDivision of Surgery, Tel Aviv Sourasky Medical Center affiliated to Tel Aviv University, Tel Aviv, Israel.
Andrew G RobertsonDepartment of Bariatric and Upper GI Surgery, University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, UK.
Sang Hyun KimDepartment of Surgery, Soonchunhyang University Seoul Hospital, Seoul, Korea.
Rudolf WeinerSana Klinikum Offenbach, Clinic for Surgery of Obesity and Metabolic Disorders, Starkenburgring 66, Offenbach am Main, Germany.
Kamal MahawarDepartment of Surgery, South Tyneside and Sunderland NHS Foundation Trust, Sunderland, UK.
Asim ShabbirDepartment of Surgery, National University Hospital, Singapore, Singapore.
Mohammad KermansaraviDepartment of Surgery, Minimally Invasive Surgery Research Center, Division of Minimally Invasive and Bariatric Surgery, Hazrat-E Fatemeh Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Reynu RajanUpper Gastrointestinal Surgery, Avisena Specialist Hospital, Shah Alam, Malaysia.
Yosuke SekiWeight Loss and Metabolic Surgery Center, Yotsuya Medical Cube, Tokyo, Japan.
Halit Eren TaskinDepartment of General Surgery, Bariatric Surgery Center, İstanbul University Cerrahpasa, Cerrahpasa Faculty of Medicine, Istanbul, Turkey.
Scott ShikoraCenter for Metabolic and Bariatric Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Edward OliverosInstitute of Surgery, St. Luke's Medical Center, Manila, Philippines.
Chetan ParmarDepartment of Surgery, Whittington Health NHS Trust, London, UK; University College London, London, UK.
Qiuye ChengDepartment of Upper Gastrointestinal Surgery, St George Private Hospital, Sydney, NSW, Australia.
Omar ThaherDepartment of Surgery, Knappschaft Kliniken University Hospital Bochum, Ruhr-University Bochum, Bochum, Germany.
Elena Ruiz-ÚcarDepartment of Metabolic, Bariatric and Endocrine Surgery, Fuenlabrada University Hospital, Madrid, Spain.
Rodolfo OviedoDepartment of Surgery, Nacogdoches Medical Center, Nacogdoches, TX, USA; University of Houston Tilman J. Fertitta Family College of Medicine, Houston, TX, USA; Sam Houston State University College of Osteopathic Medicine, Conroe, TX, USA.
Rui RibeiroCentro Multidisciplinar De Tratamento da Obesidade, Hospital Lusíadas Amadora E Lisbon, Amadora, Portugal.
Mario MusellaAdvanced Biomedical Sciences Department, Federico II University, Naples, Italy.
Almino C RamosInstitute for Metabolic Optimization, Sao Paulo, Brazil.
Seung-Wan RyuKeimyung University Dongsan Medical Centre, Daegu, Republic of Korea.
Tamer AbdelbakiGeneral Surgery, Alexandria University Faculty of Medicine, Alexandria, Egypt.
Wei Jei LeeMedical Weight Loss Center, China Medical University Shinchu Hospital, Zhubei City, Taiwan, China.
Man Pan ChanDepartment of Surgery, Yan Chai Hospital, Hong Kong, China.
Jose Eduardo Garcia FloresBariatric and Metabolic Surgery, Christus Mugerza Alta Especialidad/UDEM, Monterrey, Nuevo Leon, Mexico.
James SkinovskySurgery, HTC High Tech Surgery Association, São Vicente University Hospital, Curitiba, Brazil.
Ahmad MadkhaliDepartment of Surgery, King Saud University Medical City, Riyadh, Saudi Arabia.
Sylvia WeinerMetabolic Unit, Schiffer Campus, University of Frankfurt, Schulstr. 31, 60594 Frankfurt, Germany.
Frank TackeDepartment of Gastroenterology and Hepatology, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum (CVK) and Campus Charité Mitte (CCM), Berlin, Germany.
Wah YangDepartment of Metabolic and Bariatric Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China. Electronic address: yangwah@connect.hku.hk.
James NeubergerLiver Unit, Queen Elizabeth Hospital, Birmingham, UK. Electronic address: jamesneuberger@hotmail.co.uk.
Ming-Hua ZhengMAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China; Cixi Biomedical Research Institute, Wenzhou Medical University, Wenzhou, China; Institute of Hepatology, Wenzhou Medical University, Wenzhou, China; Key Laboratory of Diagnosis and Treatment for the Development of Chronic Liver Disease in Zhejiang Province, Wenzhou, China. Electronic address: zhengmh@wmu.edu.cn.
International Obesity Society Working Group on Steatotic Liver Disease

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laparoscopic liver biopsy (LLB) provides a way to obtain liver tissue samples under direct visual inspection of the liver surface. It complements percutaneous liver biopsy (PLB) for complex or high-risk cases where PLB cannot be performed. Clinical practices for LLB vary across centers due to the lack of international standards. To improve the procedural quality and diagnostic efficiency of LLB, a multidisciplinary panel of 45 international experts from 6 continents, including hepatology, hepatobiliary surgery, gastrointestinal surgery, and metabolic and bariatric surgery, developed this consensus statement through three rounds of a modified Delphi process. This consensus covers clinical application scenarios, high-risk clinical scenarios, preoperative preparation, surgical procedures, complication management, and discharge and quality management. It aims to promote the standardization, safety, and rational clinical application of LLB; support the management of complex cases; and facilitate the appropriate implementation of this important diagnostic procedure.

Indexed as

LaparoscopyLiverLiver DiseasesBiopsyHumansconsensus statementDelphi surveydiagnostic procedurelaparoscopic liver biopsyliver biopsyliver disease

Identifiers

PMID42173098
PMCPMC13293958

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