Evidence map›Paper›PMID 42172641›Full record

ArticleJMIR research protocols2026

Strengthening Primary Care With a Minimal Digital Ecosystem in Burkina Faso: Protocol for a Pragmatic Mixed Methods Implementation Study.

David Zombré, Joël Arthur Kiendrébéogo, Issa Kaboré, Simon Tiendrébéogo, Yamba Kafando, Michael Chaitkin, Rémi Kaboré, Charlemagne Tapsoba, Orokia Sory, Nacanabo Relwendé and 8 more

Abstract read
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Article in JMIR research protocols, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

18 authors.

David ZombréRecherche Pour la Santé et le Développement (RESADE), Secteur 28, Ouagadougou, 04 BP 8398, Burkina Faso, 226 73621620.ORCID 0000-0002-7038-4738
Joël Arthur KiendrébéogoRecherche Pour la Santé et le Développement (RESADE), Secteur 28, Ouagadougou, 04 BP 8398, Burkina Faso, 226 73621620.ORCID 0000-0002-7000-3712
Issa KaboréRecherche Pour la Santé et le Développement (RESADE), Secteur 28, Ouagadougou, 04 BP 8398, Burkina Faso, 226 73621620.ORCID 0000-0003-1568-4444
Simon TiendrébéogoRecherche Pour la Santé et le Développement (RESADE), Secteur 28, Ouagadougou, 04 BP 8398, Burkina Faso, 226 73621620.ORCID 0000-0001-5507-7564
Yamba KafandoRecherche Pour la Santé et le Développement (RESADE), Secteur 28, Ouagadougou, 04 BP 8398, Burkina Faso, 226 73621620.ORCID 0009-0008-7128-2021
Michael ChaitkinGlobal Development Division, Gates Foundation, Seattle, WA, United States.ORCID 0000-0002-9368-7651
Rémi KaboréRecherche Pour la Santé et le Développement (RESADE), Secteur 28, Ouagadougou, 04 BP 8398, Burkina Faso, 226 73621620.ORCID 0000-0003-3770-5891
Charlemagne TapsobaRecherche Pour la Santé et le Développement (RESADE), Secteur 28, Ouagadougou, 04 BP 8398, Burkina Faso, 226 73621620.ORCID 0009-0001-5801-8129
Orokia SoryRecherche Pour la Santé et le Développement (RESADE), Secteur 28, Ouagadougou, 04 BP 8398, Burkina Faso, 226 73621620.ORCID 0000-0002-6325-1195
Nacanabo RelwendéRecherche Pour la Santé et le Développement (RESADE), Secteur 28, Ouagadougou, 04 BP 8398, Burkina Faso, 226 73621620.ORCID 0000-0003-4010-0236
Noellie KonseboRecherche Pour la Santé et le Développement (RESADE), Secteur 28, Ouagadougou, 04 BP 8398, Burkina Faso, 226 73621620.ORCID 0009-0003-3737-1710
Mamadou Sani TaramRecherche Pour la Santé et le Développement (RESADE), Secteur 28, Ouagadougou, 04 BP 8398, Burkina Faso, 226 73621620.ORCID 0009-0004-4423-3946
Boureima ParéRecherche Pour la Santé et le Développement (RESADE), Secteur 28, Ouagadougou, 04 BP 8398, Burkina Faso, 226 73621620.ORCID 0009-0009-5336-1460
Wend-Timbe-Noma Arlette Raïssa ZongoRecherche Pour la Santé et le Développement (RESADE), Secteur 28, Ouagadougou, 04 BP 8398, Burkina Faso, 226 73621620.ORCID 0009-0005-7221-6630
Daliah Marie NacoulmaRecherche Pour la Santé et le Développement (RESADE), Secteur 28, Ouagadougou, 04 BP 8398, Burkina Faso, 226 73621620.ORCID 0009-0002-5441-1609
Wendyiida Bibata DerraRecherche Pour la Santé et le Développement (RESADE), Secteur 28, Ouagadougou, 04 BP 8398, Burkina Faso, 226 73621620.ORCID 0009-0004-8387-1326
Abdoul Razak HebieRecherche Pour la Santé et le Développement (RESADE), Secteur 28, Ouagadougou, 04 BP 8398, Burkina Faso, 226 73621620.ORCID 0009-0001-7606-8541
Pierre YaméogoRecherche Pour la Santé et le Développement (RESADE), Secteur 28, Ouagadougou, 04 BP 8398, Burkina Faso, 226 73621620.ORCID 0000-0001-7019-171X

Funding

Gates Foundation INV-056021
6 · The paper itself

Abstract

Background: In Burkina Faso, the Minimal Digital Ecosystem (MDE)-a suite of 9 integrated digital tools-was introduced to support key health system functions, including care delivery, financial management, medication oversight, governance, and data use. However, evidence regarding the maturity of its real-world implementation and the determinants influencing its adoption remains scarce. Objective: This pragmatic mixed methods study aims to (1) measure MDE implementation maturity across 4 dimensions (adoption, fidelity, penetration, sustainability), (2) identify multilevel determinants using the Consolidated Framework for Implementation Research (CFIR 2.0) and Normalization Process Theory (NPT), and (3) examine associations between implementation degree and primary health care (Centre de Santé et de Promotion Sociale [CSPS]) performance. Methods: We use a sequential explanatory design (quantitative → qualitative) in 4 districts covering 72 CSPSs. Phase 1 involves a cross-sectional survey of all eligible health workers, facility managers, and community health workers (estimated 612 respondents nested within facilities) using CFIR- and NPT-informed questionnaires. Following psychometric validation (exploratory/confirmatory factor analysis; reliability assessment via Cronbach α and McDonald ω), we will fit multilevel models with CSPS random intercepts and district fixed effects to (1) quantify between-facility implementation variance, (2) test associations with CFIR and NPT determinants, and (3) examine relationships with CSPS performance indicators. Phase 2 involves purposive sampling of facilities with varying implementation profiles for interviews, focus groups, and observations, analyzed using reflexive thematic analysis to explain quantitative patterns. Results: Ethics approval was obtained from Burkina Faso's National Ethics Committee (number 2023-06-136). The study was funded in June 2022 (Gates Foundation, Grant INV-056021) and is being conducted across 72 primary health care facilities in 4 districts (Manga, Sapouy, Ténado, and Ziniaré) in Burkina Faso. Qualitative data collection commenced in November 2025 and was completed in January 2026. Quantitative data collection took place from January 2023 to October 2025. As of May 2026, qualitative data collection was completed, and quantitative analyses had commenced. Psychometric analyses are underway. Conclusions: By addressing key evidence and measurement gaps in digital health implementation, this protocol will (1) generate context-specific guidance on implementing and institutionalizing a complex digital health ecosystem and (2) provide validated, ready-to-use instruments to quantify implementation at the CSPS level. Together, these outputs will help policymakers and program managers define and track "implementation success," informing-and accelerating-the scale-up and optimization of the MDE in resource-constrained settings.

Indexed as

Primary Health CareBurkina FasoCross-Sectional StudiesDigital HealthHumansPsychometricsResearch DesignSurveys and QuestionnairesBurkina FasoCFIRConsolidated Framework for Implementation Researchdigital healthimplementation sciencemixed methodsNormalization Process TheoryNPTprimary health carescale validation

Identifiers

PMID42172641
PMCPMC13197158

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.