Evidence map›Paper›PMID 42172229›Full record

ArticlePloS one2026

HIV incidence among sexually active young males and females in Kisumu County, Western Kenya.

John Owuoth, Chiaka Nwoga, Valentine Sing'oei, Adam Yates, June Otieno, Erica Broach, Qun Li, Zebiba Hassen, Seth Frndak, Michelle Imbach and 12 more

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

John OwuothHJF Medical Research International, Kisumu, Kenya.
Chiaka NwogaU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
Valentine Sing'oeiHJF Medical Research International, Kisumu, Kenya.
Adam YatesU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
June OtienoWalter Reed Army Institute of Research-Africa, Nairobi, Kenya.
Erica BroachU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
Qun LiU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
Zebiba HassenU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
Seth FrndakU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
Michelle ImbachU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
Leigh Anne EllerU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
Mark MilazzoU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
Tsedal MebrahtuU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
Hunter J SmithWalter Reed Army Institute of Research-Africa, Nairobi, Kenya.ORCID 0000-0002-3591-588X
Nathanial K CopelandWalter Reed Army Institute of Research-Africa, Nairobi, Kenya.
Jessica CowdenWalter Reed Army Institute of Research-Africa, Nairobi, Kenya.
Dale J HuDivision of AIDS, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, Maryland, United States of America.
Merlin L RobbHenry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, United States of America.
Julie A AkeU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
Christina S PolyakU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.
Trevor A CrowellU.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America.ORCID 0000-0001-5947-265X
RV393 Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHIV prevalence in Kisumu County, Kenya, is over four times the national average. We estimated HIV incidence among adults with multiple sexual partners and identified risk factors associated with HIV acquisition.

methodsWe enrolled adults aged 18-35 years reporting ≥2 sexual partners in the prior 3 months, recruiting primarily from villages with fisherfolk. HIV counseling and testing were performed every 3 months for up to 24 months. Demographic, health, sexual, and behavior questionnaires were administered every 6 months. Enrollment characteristics were compared between participants who did and did not acquire HIV using chi-squared tests. Bivariable Cox proportional hazards models estimated hazard ratios (HRs) and 95% confidence intervals (CIs) for potential risk factors.

resultsBetween January 2017 and August 2021, 619 participants without HIV were enrolled, of whom 45% were female, 47% were ≥25 years old, 66% were single or widowed, and 46% had some secondary education. Eleven HIV seroconversions occurred over 1117.9 person-years (PY; incidence 9.84/1000 PY [95% CI: 5.22-17.03]), including eight in the first year of follow-up (13.84/1000 PY). Risk factors in unadjusted analyses included ≥4 sexual partners (HR 4.39 [95% CI 1.10-17.55]) and forced sexual activity (HR 9.15 [95% CI 1.17-71.51]).

conclusionHIV incidence was lower than expected, possibly reflecting prevention efforts or COVID-19-related behavior changes. Lower incidence in later follow-up may indicate a cohort effect from regular counseling. Increasing ART coverage and pre-exposure prophylaxis may have decreased HIV incidence in fishing communities of Western Kenya.

Indexed as

HIV InfectionsSexual BehaviorAdolescentAdultFemaleHumansIncidenceKenyaMaleRisk FactorsSexual PartnersYoung Adult

Identifiers

PMID42172229
PMCPMC13196977

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.