Evidence map›Paper›PMID 42172144›Full record

ArticleeLife2026

In situ mutational screening and CRISPR interference define

Gustavo Aguilar, Michèle E Sickmann, Dimitri Bieli, Gordian Born, Markus Affolter, Martin Müller

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gustavo Aguilar *Growth and Development, Biozentrum, Spitalstrasse 41, University of Basel, Basel, Switzerland.ORCID 0000-0002-0524-9388
Michèle E Sickmann *Growth and Development, Biozentrum, Spitalstrasse 41, University of Basel, Basel, Switzerland.
Dimitri BieliGrowth and Development, Biozentrum, Spitalstrasse 41, University of Basel, Basel, Switzerland.
Gordian BornGrowth and Development, Biozentrum, Spitalstrasse 41, University of Basel, Basel, Switzerland.
Markus AffolterGrowth and Development, Biozentrum, Spitalstrasse 41, University of Basel, Basel, Switzerland.ORCID 0000-0002-5171-0016
Martin MüllerGrowth and Development, Biozentrum, Spitalstrasse 41, University of Basel, Basel, Switzerland.ORCID 0000-0002-0667-9574

Funding

Swiss National Science Foundation 310030_192659Swiss National Science Foundation 310030B_176400
6 · The paper itself

Abstract

The establishment of tissue axes is fundamental during embryonic development. In the

Indexed as

DrosophilaDrosophila melanogasterDrosophila ProteinsGene Expression Regulation, DevelopmentalHomeodomain ProteinsTranscription FactorsWings, AnimalAnimalsBody PatterningClustered Regularly Interspaced Short Palindromic RepeatsCRISPR-Cas SystemsDNA Mutational AnalysisEnhancer Elements, GeneticLIM-Homeodomain ProteinsMutationap protein, DrosophilaDrosophila ProteinsHomeodomain ProteinsLIM-Homeodomain ProteinsTranscription FactorsCRISPRidCas9developmental biologydevelopmental boundaryD. melanogasterenhancergeneticsgenome engineeringgenomicswing development

Identifiers

PMID42172144
PMCPMC13197166

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.