Evidence map›Paper›PMID 42172134›Full record

ArticleACS infectious diseases2026

F2F-202, a Selective Histone Deacetylase 6 (HDAC6) Inhibitor, Behaves as an Arrow with Multiple Tips against Azole-Resistant

Simona Barone, Baptiste Mateu, Marialuisa Piccolo, Anna Guadagni, Carlo Irace, Francesca Lembo, Vincenzo Summa, Elisabetta Buommino, Margherita Brindisi

Abstract read
In one paragraph

Article in ACS infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Simona BaroneDepartment of Pharmacy, Department of Excellence 2023-2027, University of Naples Federico II, via D. Montesano 49, 80131 Naples, Italy.
Baptiste MateuDepartment of Pharmacy, Department of Excellence 2023-2027, University of Naples Federico II, via D. Montesano 49, 80131 Naples, Italy.
Marialuisa PiccoloDepartment of Pharmacy, Department of Excellence 2023-2027, University of Naples Federico II, via D. Montesano 49, 80131 Naples, Italy.
Anna GuadagniDepartment of Pharmacy, Department of Excellence 2023-2027, University of Naples Federico II, via D. Montesano 49, 80131 Naples, Italy.
Carlo IraceDepartment of Pharmacy, Department of Excellence 2023-2027, University of Naples Federico II, via D. Montesano 49, 80131 Naples, Italy.
Francesca LemboDepartment of Pharmacy, Department of Excellence 2023-2027, University of Naples Federico II, via D. Montesano 49, 80131 Naples, Italy.
Vincenzo SummaDepartment of Pharmacy, Department of Excellence 2023-2027, University of Naples Federico II, via D. Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-6288-2681
Elisabetta BuomminoDepartment of Pharmacy, Department of Excellence 2023-2027, University of Naples Federico II, via D. Montesano 49, 80131 Naples, Italy.
Margherita BrindisiDepartment of Pharmacy, Department of Excellence 2023-2027, University of Naples Federico II, via D. Montesano 49, 80131 Naples, Italy.ORCID 0000-0001-9119-3773

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungal infections are increasingly threatening public health due to the onset of multidrug-resistant fungal strains. Accordingly, the incidence of chemoresistant

Indexed as

Antifungal AgentsAzolesCandida albicansDrug Resistance, FungalHistone Deacetylase InhibitorsHyphaeOxidative StressDrug SynergismFungal ProteinsGene Expression Regulation, FungalHistone DeacetylasesMicrobial Sensitivity TestsVoriconazoleAntifungal AgentsAzolesFungal ProteinsHistone Deacetylase InhibitorsHistone DeacetylasesVoriconazoleC. albicanschemoresistanceHda1histone deacetylase 6synergismyeast-to-hyphae transition

Identifiers

PMID42172134
PMCPMC13270531

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.