Evidence map›Paper›PMID 42171957›Full record

ReviewCurrent pain and headache reports2026

Regional Anesthesia for Penile Inversion Vaginoplasties.

Jevaughn S Davis, Ayomide Ogunsakin, Boladale Ashiru, Amber Haywood, Akhil Patel, Crystal Adams

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current pain and headache reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jevaughn S DavisDepartment of Anesthesiology and Critical Care, George Washington School of Medicine and Health Sciences, Washington, DC, USA. jevdavis@mfa.gwu.edu.
Ayomide OgunsakinMedical Student, Howard University School of Medicine, Washington, DC, USA.
Boladale AshiruResident Physician, Department of Anesthesiology and Critical Care, George Washington School of Medicine and Health Sciences, Washington, DC, USA.
Amber HaywoodMedical Student, The George Washington University School of Medicine, Washington, DC, USA.
Akhil PatelDepartment of Anesthesiology and Critical Care, George Washington School of Medicine and Health Sciences, Washington, DC, USA.
Crystal AdamsDepartment of Anesthesiology and Critical Care, George Washington School of Medicine and Health Sciences, Washington, DC, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewPenile inversion vaginoplasty is a complex procedure performed as part of gender-affirming care. It is a highly complex procedure involving extensive genital deconstruction and reconfiguration. As a result, effective post-operative pain control is a central component of perioperative care in this patient population. This review aims to synthesize and consolidate the current evidence on regional anesthesia techniques for postoperative pain management in patients undergoing penile inversion vaginoplasty. RECENT

findingsEffective pain management is critical, as inadequate control has been associated with decreased patient satisfaction, prolonged hospital stays, increased opioid consumption, delayed ambulation, and higher overall healthcare costs. Pain management strategies emphasize multimodal analgesia, incorporating acetaminophen, nonsteroidal anti-inflammatory drugs, opioids (oral and intravenous), local anesthetic infiltration by surgeons, nerve blocks, and neuraxial anesthesia. Within Enhanced Recovery After Surgery (ERAS) protocols, regional anesthesia, including neuraxial techniques and peripheral nerve blocks, has gained prominence and popularity, with substantial evidence demonstrating a reduction in overall opioid consumption and opioid-related adverse effects across a wide range of surgical procedures. Regional anesthesia is a key component of multimodal analgesia and ERAS pathways in penile inversion vaginoplasty. Consolidating current evidence may help clarify its role in optimizing postoperative pain control, reducing opioid exposure, and improving recovery and patient-centered outcomes in this population.

Indexed as

Anesthesia, ConductionGender-Affirming SurgeryPain ManagementPenisPostoperative PainVaginaFemaleHumansMaleNerve BlockAnalgesiaGender Affirming CarePain ManagementPenile InversionRegional AnesthesiaVaginoplasty

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.