Evidence map›Paper›PMID 42171895›Full record

ReviewActa neurologica Belgica2026

Breaking the seizure cycle: Belgian expert consensus on the diagnostics and treatment of acute convulsive seizures in children.

A Aeby, B Ceulemans, K Jansen, A Jansen, L Lagae, P Leroy, A-S Schoonjans, H Verhelst, M R Cilio

Abstract readConsensus StatementReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Acta neurologica Belgica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

A AebyDepartment of Paediatric Neurology, Hôpital Universitaire des Enfants Reine Fabiola (HUDERF) et Hôpital Erasme, Member of European Reference Network EPICARE, Université Libre de Bruxelles (ULB), Hôpital Universitaire de Bruxelles (H.U.B), Brussels, Belgium. alec.aeby@hubruxelles.be.
B CeulemansDepartment of Pediatric Neurology, Antwerp University Hospital (UZA), Edegem, Belgium.
K JansenSection Pediatric Neurology, Department Development and Regeneration, Member of European Reference Network EPICARE, University Hospitals KU Leuven, Leuven, Belgium.
A JansenDepartment of Pediatric Neurology, Antwerp University Hospital (UZA), Edegem, Belgium.
L LagaeDepartment of Pediatric Neurology, Antwerp University Hospital (UZA), Edegem, Belgium.
P LeroyDepartement of Pediatric Neurology, CHU de Liège, Liège, Belgium.
A-S SchoonjansDepartment of Pediatric Neurology, Antwerp University Hospital (UZA), Edegem, Belgium.
H VerhelstDepartment of Paediatrics, Division Paediatric Neurology, Ghent University Hospital, Ghent, Belgium.
M R CilioDivision of Child Neurology, Department of Pediatrics, Institute of Neuroscience (IoNS), Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSeizures are the most common neurological emergency in children. Heterogeneous causes, subtypes, and varying treatment responses make seizures a complex and often unpredictable challenge for clinicians. The management of acute seizures in children, particularly in the outpatient setting, received relatively limited attention in international treatment guidelines. Prompt and proper management in the acute setting, may prevent hospitalization as well as long-term neurological and developmental consequences.

methodsAn expert consensus panel was convened to develop comprehensive and practical guidance for the early recognition, diagnostic evaluation, and management of acute convulsive seizures in children and adolescents. Recommendations were formulated through a structured review of the most recent scientific literature, current clinical guidelines, and expert opinion. Emphasis was placed on generating clear, actionable recommendations to support healthcare professionals in the rapid identification and effective treatment of acute convulsive seizures in pediatric populations.

resultsThis report specifically focuses on the first 5-10 min from seizure onset, which usually corresponds to the outpatient setting, including the initial steps of the inpatient treatment pathway for acute convulsive seizures in children and adolescents.

conclusionsThis expert review provides actionable insights for healthcare professionals managing pediatric seizures, emphasizing the importance of a rapid and effective treatment for acute convulsive seizures.

Indexed as

AnticonvulsantsSeizuresAcute DiseaseAdolescentChildHumansAnticonvulsantsBenzodiazepineFebrile seizureLevetiracetamOutpatientRecommendations

Identifiers

PMID42171895
PMCPMC13242445

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.