ArticleJournal of neurology2026
Radiomic hemorrhage roundness predicts outcome beyond the ICH score in deep intracerebral hemorrhage with IVH.
Article in Journal of neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAccurate prognostication in deep supratentorial intracerebral hemorrhage (ICH) remains challenging. Hematoma volume is a key determinant of outcome and a component of the ICH Score. Whether radiomics-derived shape features provide prognostic information beyond volumetric burden and clinical risk scores remains unclear. We investigated the association between radiomic shape characteristics of basal ganglia hemorrhage (BGH) and intraventricular hemorrhage (IVH) with in-hospital mortality and unfavorable functional outcome.
methodsWe retrospectively analyzed 50 patients with deep supratentorial ICH and IVH. Semi-automated segmentations were used to extract radiomic features (roundness, elongation, flatness, Feret diameter, surface area) and volumetric parameters. Logistic regression models were constructed for in-hospital mortality and unfavorable functional outcome (mRS 5-6 at discharge; secondary definition mRS 4-6), with collinearity assessment guiding feature selection. Model discrimination was evaluated using receiver operating characteristic curves with DeLong comparisons. Secondary models incorporated the ICH Score. Calibration and internal validation were assessed using the Hosmer-Lemeshow test and bootstrap resampling (1000 iterations).
resultsFor in-hospital mortality, BGH roundness showed discrimination comparable to BGH volume (AUC 0.742 vs 0.738). In multivariable analysis, lower roundness remained independently associated with mortality after adjustment for the ICH Score (OR 0.20 per 0.1 increase; 95% CI 0.04-0.66; p = 0.021), whereas volume was no longer significant. The combined model achieved an AUC of 0.866 versus 0.813 for the ICH Score (DeLong p = 0.28). IVH-derived shape parameters were not associated. For unfavorable outcome, BGH volume remained strongest predictor.
conclusionsRadiomic hemorrhage roundness may provide complementary prognostic information beyond hematoma volume and the ICH Score in deep ICH with IVH.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.