Evidence map›Paper›PMID 42171578›Full record

ArticleJACC. Case reports2026

Tricuspid Valve Regurgitation Manifesting in Gastrointestinal Symptoms.

Ninoshka Pérez-Soto, Angélica Fregoso-Sánchez, Jorge Javier Miguel-González, Anna Greti Everding-Rodríguez, Alex Daniel Pacheco-Bouthiller, Benigno Ferreira-Piña, Adriana González-Martínez, Óscar Sergio Lomelí-Sánche

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ninoshka Pérez-SotoResearch Department, Instituto Cardiovascular de Mínima Invasión, Zapopan, Jalisco, México; Research Department, Universidad Autónoma de Guadalajara - School of Medicine, International Program.
Angélica Fregoso-SánchezResearch Department, Instituto Cardiovascular de Mínima Invasión, Zapopan, Jalisco, México.
Jorge Javier Miguel-GonzálezResearch Department, Instituto Cardiovascular de Mínima Invasión, Zapopan, Jalisco, México.
Anna Greti Everding-RodríguezResearch Department, Instituto Cardiovascular de Mínima Invasión, Zapopan, Jalisco, México.
Alex Daniel Pacheco-BouthillerResearch Department, Instituto Cardiovascular de Mínima Invasión, Zapopan, Jalisco, México.
Benigno Ferreira-PiñaResearch Department, Instituto Cardiovascular de Mínima Invasión, Zapopan, Jalisco, México.
Adriana González-MartínezResearch Department, Instituto Cardiovascular de Mínima Invasión, Zapopan, Jalisco, México.
Óscar Sergio Lomelí-SáncheResearch Department, Instituto Cardiovascular de Mínima Invasión, Zapopan, Jalisco, México. Electronic address: oscarlomeli11@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTricuspid regurgitation has a typical presentation coexisting with right heart failure symptoms and is challenging to diagnose, with extracardiac manifestations often overlooked. CASE SUMMARY: A 35-year-old woman had a history of mixed neurocardiogenic syncope. She received a pacemaker at age 11; 13 years later, she developed lead dysfunction. As pacing was no longer required, the leads were removed. She subsequently developed asymptomatic tricuspid regurgitation and experienced gastrointestinal symptoms, which were initially attributed to irritable bowel syndrome, with a low Gastrointestinal Quality of Life Index (GIQLI) score. Biological valve replacement improved gastrointestinal symptoms and GIQLI score. Later, a mechanical valve was implanted owing to bioprosthesis deterioration, resulting in further clinical and GIQLI score improvement. DISCUSSION: Severe tricuspid regurgitation may cause visceral venous congestion, intestinal edema, dysbiosis, hypoperfusion, and inflammation, producing gastrointestinal symptoms. TAKE-HOME MESSAGE: This case emphasizes the importance of considering visceral venous congestion symptoms, such as gastrointestinal manifestations, in the assessment and management of severe tricuspid regurgitation.

Indexed as

bowel diseasescase reporttricuspid regurgitationvalve diseases, visceral venous congestion

Identifiers

PMID42171578
PMCPMC13350373

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.