Evidence map›Paper›PMID 42171569›Full record

ArticleJACC. Case reports2026

Focal Pulsed Field Ablation and Strategic Upsizing in Concomitant Atrial Fibrillation Ablation and Left Atrial Appendage Occlusion.

Tesfatsiyon Ergando, Mariam Tarek Desouki, Mathew Katsiyiannis, Ali Bahbah, Kerollos Abdelsayed, Dawn Witt, Efrah Hussein, Jay Sengupta, Nadira Hamid

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tesfatsiyon ErgandoMinneapolis Heart Institute, Minneapolis, Minnesota, USA; Hennepin Health, Minneapolis, Minnesota, USA.
Mariam Tarek DesoukiThe Joseph F. Novogratz Family Heart Rhythm Science Centre, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA. Electronic address: mariam.desouki@allina.com.
Mathew KatsiyiannisThe Joseph F. Novogratz Family Heart Rhythm Science Centre, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA.
Ali BahbahThe Joseph F. Novogratz Family Heart Rhythm Science Centre, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA; Department of Medicine, University of California-San Francisco, Fresno Program, Fresno, California, USA.
Kerollos AbdelsayedThe Joseph F. Novogratz Family Heart Rhythm Science Centre, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA.
Dawn WittThe Joseph F. Novogratz Family Heart Rhythm Science Centre, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA.
Efrah HusseinThe Joseph F. Novogratz Family Heart Rhythm Science Centre, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA.
Jay SenguptaThe Joseph F. Novogratz Family Heart Rhythm Science Centre, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA.
Nadira HamidMinneapolis Heart Institute, Minneapolis, Minnesota, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConcomitant atrial fibrillation ablation and left atrial appendage (LAA) occlusion are increasingly considered in patients with elevated thromboembolism and bleeding risk. Emerging data suggest a higher incidence of peridevice leak with pulsed field ablation (PFA). CASE SUMMARY: Two patients underwent concomitant PFA with the Sphere-9 catheter (Affera/Medtronic) and Watchman FLX Pro (Boston Scientific); postablation LAA changes were managed with tailored upsizing in one case and standard sizing in the other. At 6 months, both maintained sinus rhythm on antiplatelet therapy with no thromboembolic or bleeding events, and cardiac computed tomography confirmed well-seated devices with peridevice leak ≤2 mm. DISCUSSION: These are the first reported cases of concomitant LAA occlusion with Watchman FLX Pro and Sphere-9 PFA. Postablation LAA anatomical changes influenced device selection, and larger studies are needed to validate these findings. TAKE-HOME MESSAGES: Focal PFA led to specific, observable changes in LAA anatomy, directly affecting device sizing decisions. Tailoring device sizing to account for postablation LAA remodeling-using standard sizing or upsizing-may optimize device seal and compression.

Indexed as

atrial fibrillationLAAOpulsed field ablationwatchman FLX Pro

Identifiers

PMID42171569
PMCPMC13326263

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.