Evidence map›Paper›PMID 42171441›Full record

ArticleAngewandte Chemie (International ed. in English)2026

Hierarchically Chiral Silver Nanoclusters Mediated Enantioselective Glutathione Depletion and Intracellular Self-Assembly for Enhanced Anticancer Therapy.

Xuejuan Wang, Xirui Wu, Yue Zhao, Xiangyang Zhang, Jianfeng Zhao, Miaolong Li, Guangbao Yang, Guofeng Liu

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xuejuan WangShanghai Key Laboratory of Chemical Assessment and Sustainability, School of Chemical Science and Engineering, Advanced Research Institute, Tongji University, Shanghai, P. R. China.
Xirui WuState Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, P. R. China.
Yue ZhaoSchool of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, Singapore, Singapore.
Xiangyang ZhangShanghai Key Laboratory of Chemical Assessment and Sustainability, School of Chemical Science and Engineering, Advanced Research Institute, Tongji University, Shanghai, P. R. China.
Jianfeng ZhaoState Key Laboratory of Catalysis, Dalian National Laboratory For Clean Energy, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.
Miaolong LiShanghai Key Laboratory of Chemical Assessment and Sustainability, School of Chemical Science and Engineering, Advanced Research Institute, Tongji University, Shanghai, P. R. China.
Guangbao YangState Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, P. R. China.ORCID 0000-0001-6180-5310
Guofeng LiuShanghai Key Laboratory of Chemical Assessment and Sustainability, School of Chemical Science and Engineering, Advanced Research Institute, Tongji University, Shanghai, P. R. China.ORCID 0000-0003-1911-8546

Funding

National Natural Science Foundation of China 22101208National Natural Science Foundation of China 22471198National Natural Science Foundation of China 52372270Natural Science Foundation of Jiangsu Province BK20240151
6 · The paper itself

Abstract

Chiral nanomedicine design benefits from understanding enantioselective interactions between hierarchically chiral nanoclusters and tumor biomarkers. In this study, we synthesized a pair of silver nanoclusters with bilevel chirality, designated as D-Ag

Indexed as

Antineoplastic AgentsGlutathioneMetal NanoparticlesSilverAnimalsCell Line, TumorDrug Screening Assays, AntitumorHumansPolyethylene GlycolsReactive Oxygen SpeciesStereoisomerismAntineoplastic AgentsGlutathionePolyethylene GlycolsReactive Oxygen SpeciesSilverchiral nanoclusterenantioselective glutathione depletionferroptosisintracellular self‐assemblyreactive oxygen species

Identifiers

PMID42171441
PMCPMC13360727

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.