Evidence map›Paper›PMID 42171364›Full record

ArticleClinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery2026

Compliance and Effectiveness of the Scottish Referral Guidelines for Suspected Head and Neck Cancer: A Comparative Audit of 7088 Referrals.

Oliver G Denton, Ryan Morrison, Baryab Zahra, Ivy Drake, Jenny Montgomery

Abstract readComparative Study
In one paragraph

Article in Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Oliver G DentonDepartment of Otolaryngology, Head and Neck Surgery, Queen Elizabeth University Hospital, Glasgow, Scotland, UK.ORCID https://orcid.org/0000-0003-1314-8904
Ryan MorrisonDepartment of Medicine, University of Glasgow, Glasgow, Scotland, UK.ORCID https://orcid.org/0009-0006-6499-8684
Baryab ZahraDepartment of Otolaryngology, Head and Neck Surgery, Queen Elizabeth University Hospital, Glasgow, Scotland, UK.ORCID https://orcid.org/0000-0001-9451-0789
Ivy DrakeDepartment of Otolaryngology, Head and Neck Surgery, Queen Elizabeth University Hospital, Glasgow, Scotland, UK.ORCID https://orcid.org/0000-0002-1204-4110
Jenny MontgomeryDepartment of Otolaryngology, Head and Neck Surgery, Queen Elizabeth University Hospital, Glasgow, Scotland, UK.ORCID https://orcid.org/0000-0001-5000-4913

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn Scotland, patients with suspected head and neck cancer are referred based on the Scottish Referral Guidelines for Suspected Cancer (SRGSC). These were most recently updated in 2014 and 2019. A study using 2015-2016 data reported a compliance rate with the 2014 guidance of 55.1% and an all-cancer detection rate of 11.6% (8.6% primary head and neck cancer). This audit assessed referral compliance with the 2019 SRGSC and investigated what effect this update had on rates of head and neck cancer detection.

methodsAll 'urgent suspicion of cancer' referrals to the ENT department in the National Health Service Greater Glasgow and Clyde (NHS GGC) for 2021-2022 were audited and compared to corresponding data from 2015 to 2016.

resultsThe number of referrals increased by 110% between 2015-2016 and 2021-2022. SRGSC compliance in referral letters was 72.5%, but only 48.9% when those patients were assessed in the ENT clinic. The all-cancer detection rate was 8.6% (6.2% primary head and neck cancer). The most common reasons for referral were neck lump (28%), persistent hoarseness (15%), and persistent throat pain (11%). The most common primary head and neck cancer sites were oropharynx (18%), larynx (17%), and thyroid (11%). There were significant differences between the 2015-2016 and 2021-2022 cohorts in age at referral, sex, and risk factors.

conclusionCompared to corresponding data from 2015 to 2016, there is increased workload in 'urgent suspicion of cancer' clinic for fewer cancer diagnoses. When compliant, the SRGSHNC criteria are a valuable predictive tool for cancer diagnosis.

Indexed as

Early Detection of CancerGuideline AdherenceHead and Neck NeoplasmsPractice Guidelines as TopicReferral and ConsultationAdultAgedAged, 80 and overFemaleHumansMaleMedical AuditMiddle AgedScotlandearly diagnosis of cancerguideline adherencehead and neck neoplasmsreferral

Identifiers

PMID42171364
PMCPMC13432678

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.