Evidence map›Paper›PMID 42170912›Full record

ArticleBiochemistry2026

Peptide Mimetic Platform for Activity Profiling of Mycobacterial l,d-Transpeptidases.

Karl L Ocius, Rachel E Sanborn, Ananya Naick, Leighanne A Brammer Basta, Marcos M Pires

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Karl L OciusDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.ORCID 0009-0008-0578-8964
Rachel E SanbornChemistry Department, United States Naval Academy, Annapolis, Maryland 21402, United States.
Ananya NaickDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.
Leighanne A Brammer BastaChemistry Department, United States Naval Academy, Annapolis, Maryland 21402, United States.ORCID 0000-0002-4121-5505
Marcos M PiresDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.ORCID 0000-0002-5676-0725

Funding

Unraveling Bacterial Cell Wall Biosynthesis and Sensing via Synthetic AnalogsR35GM124893 · NIGMS · UNIVERSITY OF VIRGINIA · PI Marcos M. Pires · 2017 to 2026
$3.6M
Bacterial and Molecular Determinants of Mycobacterial ImpermeabilityR01AI179080 · NIAID · UNIVERSITY OF VIRGINIA · PI Marcos M. Pires, Mary Sloan Siegrist · 2023 to 2026
$2.9M
Structural Determinants of Permeation Barriers in Escherichia coliR01AI178975 · NIAID · UNIVERSITY OF VIRGINIA · PI PIRES, MARCOS M. · 2023 to 2024
$1.2M
NIAID NIH HHS R01 AI178975NIAID NIH HHS R01 AI179080NIGMS NIH HHS R35 GM124893
6 · The paper itself

Abstract

Antimicrobial resistance poses major therapeutic challenges, particularly for multidrug-resistant mycobacterial infections caused by

Indexed as

Bacterial ProteinsMycobacterium smegmatisPeptidesPeptidyl TransferasesAnti-Bacterial Agentsbeta Lactam AntibioticsMycobacterium tuberculosisPeptidoglycanAnti-Bacterial AgentsBacterial Proteinsbeta Lactam AntibioticsPeptidesPeptidoglycanPeptidyl Transferases

Identifiers

PMID42170912
PMCPMC13235563

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.