Evidence map›Paper›PMID 42170769›Full record

ArticleThe journal of nursing research : JNR2026

Factors Associated With Medication Safety Competence Among Clinical Nurses in China: A Latent Profile Analysis.

Ping Zhang, Genzhen Yu, Rong Xu, Shuai Cao, Lin Mo, Yang Liu, Yujie Wu

Abstract readMulticenter Study
In one paragraph

Article in The journal of nursing research : JNR, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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7 authors.

Ping ZhangDepartment of Nursing, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Genzhen YuDepartment of Nursing, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID 0009-0004-9676-3180
Rong XuDepartment of Nursing, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Shuai CaoDepartment of Nursing, Xiangyang Central Hospital, Xiangyang, China.
Lin MoOutpatient Department, Children's Hospital of Chongqing Medical University, Chongqing, China.
Yang LiuDepartment of Hematological and Oncology, Children's Hospital of Chongqing Medical University, Chongqing, China.
Yujie WuDepartment of Nursing, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Funding

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6 · The paper itself

Abstract

backgroundNurses can promote medication safety. However, the main factors affecting their ability to do so are uncertain. PURPOSE: In this study, a person-centered approach was employed to analyze the latent profiles of medication safety competence in clinical nurses in China and to identify the significant influencing factors.

methodsA multicenter cross-sectional online survey was conducted. From January 17 to February 18, 2024, 1,228 nurses (mean age=33.52, SD =7.55; 97.20% female) were recruited from several hospitals in the Chinese provinces of Hubei, Chongqing, and Guangzhou and enrolled as participants. The Critical Thinking Diagnostic Scale and Medication Safety Competence Scale were used in collecting study data. Mplus 8.3 software was adopted for the latent profile analysis to clarify the medication safety competence subgroups. SPSS 24.0 software was employed to perform the analysis of variance (ANOVA), Pearson's Chi-square analysis, and logistic regression analysis to examine the factors associated with medication safety competence.

resultsFour profiles were derived from the latent profile analysis: Profile 1 (low medication safety competence; 9%), Profile 2 (medium low medication safety competence; 8%), Profile 3 (medium high medication safety competence; 40%), and Profile 4 (high medication safety competence; 44%). The total critical thinking score was identified as a positive predictor of profile affiliation. The results of the regression analysis found that, compared with Profile 4, being a junior nurse ( OR =2.341, 95% CI [1.005, 5.450]), having no self-perceived nursing achievement ( OR =6.205, 95% CI [2.084, 18.473]), and occasionally having self-perceived nursing achievement ( OR =7.495, 95% CI [3.419, 16.430]) increased the likelihood of being in Profile 1; that having no history of medication error ( OR =0.408, 95% CI [.177, .938]) decreased the likelihood of being in Profile 1; that having 11-15 years of work experience ( OR =2.239, 95% CI [1.166, 4.299]) and occasionally having self-perceived nursing achievement ( OR =3.102, 95% CI [1.074, 8.953]) increased the likelihood of being in Profile 3; and that being a supervisor nurse ( OR =0.404, 95% CI [.242, .728]) decreased the likelihood of being in Profile 3.

conclusionsBased on the results, the medication safety competence of nurses in China may be divided into four subgroups. Having a higher critical thinking score, a professional title (supervisor nurse or above), self-perceived nursing achievement (often/always), and no history of medication error all increase the likelihood of being in Profile 4. The findings provide a reference for nursing managers when formulating continuing education to promote medication safety competence. The factors associated with the various profiles identified in this study may facilitate the development of better-tailored intervention strategies.

Indexed as

Clinical CompetenceMedication ErrorsNursesPatient SafetyAdultChinaCross-Sectional StudiesFemaleHumansMaleSurveys and Questionnairesclinical nurseslatent profile analysismedication safetymedication safety competence

Identifiers

PMID42170769
PMCPMC13200906

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