ArticleThe Veterinary record2026
The effect of romifidine on endoscopic grading of laryngeal function in horses.
Article in The Veterinary record, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo our knowledge, the effect of sedation with romifidine on the grading of laryngeal function in horses has not been studied. Our objective was to examine the effects of romifidine on the grading of laryngeal function and the cross-sectional area of the rima glottis (CSARG).
methodsTen horses underwent three endoscopic examinations of the larynx: once while unsedated (group R1), once after being sedated with romifidine (0.04 mg/kg intravenously; group R2) and once again, while still sedated, after receiving a repeat dose of romifidine (0.08 mg/kg intravenously, total dose; group R3). The recorded examinations were randomised and examined by three blinded reviewers who graded laryngeal function. The CSARG was measured from still images obtained during peak inspiration.
resultsSedation had no significant effect on the endoscopic laryngeal function grade assigned. There was no statistical difference in CSARG between Groups R1 and R2 (p = 0.164). Significant reduction in CSARG was noted between Groups R1 and R3 (p < 0.001) and Groups R2 and R3 (p = 0.045). LIMITATIONS: The low number of horses examined may have resulted in the analyses being insufficiently powered. As such, the findings should be interpreted cautiously.
conclusionA dose of 0.04 mg/kg romifidine administered intravenously had no significant effect on horses' laryngeal function grade and CSARG.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.