ArticleTurkish journal of chemistry2026
Sensitive stripping voltammetric determination of an anthracene-isatin Schiff base in biological samples.
Article in Turkish journal of chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the present study, the electrochemical behavior and quantitative determination of the Schiff base 3-[(anthracen-2-yl)imino]-5-nitro-1,3-dihydro-2H-indol-2-one (ANT) were investigated for the first time using voltammetric techniques at a glassy carbon electrode. The effects of solvent composition, pH, and scan rate on the redox behavior of ANT were systematically evaluated. The compound exhibited an irreversible oxidation process governed by adsorption-controlled kinetics. Quantitative analysis was conducted using differential pulse stripping voltammetry (AdS-DPV) and square-wave stripping voltammetry (AdS-SWV) under optimized conditions. Both methods exhibited linear responses over the concentration range of 0.2-8.0 μM, with limits of detection of 0.0366 μM and 0.0433 μM for AdS-DPV and AdS-SWV, respectively. The precision of the methods was confirmed through intra- and interday measurements, with relative standard deviations below 1.73%. Recovery studies performed in protein-free human serum yielded 99.78% and 99.52% recoveries for AdS-DPV and AdS-SWV, respectively, demonstrating their applicability to biological matrices. Mechanistic studies using 5-nitroisatin and indomethacin as model compounds indicated that ANT predominantly undergoes oxidation at the anthracene core, an outcome influenced by the nitro group, rather than at the isatin moiety. Collectively, the results reveal the developed voltammetric procedures to be simple, selective, sensitive, and reproducible, providing robust and reliable tools for the electrochemical analysis of this anthracene-isatin Schiff base derivative in biological matrices.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.