Investigation of the enzyme-inhibitory, antibacterial, and anticancer properties of metal phthalocyanines.

Meryem Topal, Fevzi Topal, Fırat Yilmaz, Esra Bulut Atalay, Ümit Muhammet Koçyiğit, Emre Güzel

Abstract read

In one paragraph

Article in Turkish journal of chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Meryem TopalVocational School of Health Services, Department of Medical Services and Techniques, Gumushane University, Gümüşhane, Turkiye.ORCID https://orcid.org/0000-0002-2107-8603

Fevzi TopalDepartment of Nutrition and Dietetics, Faculty of Health Sciences, Gumushane University, Gümüşhane, Turkiye.ORCID https://orcid.org/0000-0002-2443-2372

Fırat YilmazDepartment of Food Engineering, Faculty of Engineering and Natural Sciences, Gumushane University, Gümüşhane, Turkiye.ORCID https://orcid.org/0000-0003-3633-0012

Esra Bulut AtalayDepartment of Biochemistry, Faculty of Science, Sivas Cumhuriyet University, Sivas, Turkiye.ORCID https://orcid.org/0000-0002-1615-0535

Ümit Muhammet KoçyiğitDepartment of Biochemistry, Faculty of Pharmacy, Sivas Cumhuriyet University, Sivas, Turkiye.ORCID https://orcid.org/0000-0001-8710-2912

Emre GüzelDepartment of Engineering Fundamental Sciences, Faculty of Technology, Sakarya University of Applied Sciences, Sakarya, Turkiye.ORCID https://orcid.org/0000-0002-1142-3936

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, the enzyme inhibitory, antibacterial, and anticancer activities of a phthalonitrile derivative and its metal phthalocyanines (Pcs; indium, zinc, copper, cobalt, and manganese; 1-6) were investigated. The cobalt and manganese Pcs were synthesized for the first time in this study. The inhibitory activities of the symmetric Pcs, which were expected to interact with acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) via their 4-(isopropylbenzyl)oxy substituents through host-guest interactions, were investigated. More selective inhibition of AChE than BChE was observed for these compounds. For AChE, CoPc was identified as the most potent inhibitor (IC

Indexed as

Acetylcholinesteraseantibacterial activityanticancer activitybutyrylcholinesterasephthalocyanine

Identifiers

PMID42170625

DOI10.55730/1300-0527.3788

PMCPMC13189370

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.