Evidence map›Paper›PMID 42170569›Full record

ReviewTranslational breast cancer research : a journal focusing on translational research in breast cancer2026

Chinese Society of Clinical Oncology breast cancer expert consensus on the diagnosis and treatment of breast cancer brain metastasis (2025).

Tao Wang, Jiayi Chen, Jin Yang, Minjie Fu, Wei Hua, Wang Jia, Yueping Liu, Biyun Wang, Min Yan, Chunfang Hao and 8 more

Abstract readReview
In one paragraph

Review in Translational breast cancer research : a journal focusing on translational research in breast cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Tao Wang *Senior Department of Oncology, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Jiayi Chen *Department of Radiotherapy, Ruijin Affiliated Hospital of Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jin YangDepartment of Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Minjie FuDepartment of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Wei HuaDepartment of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Wang JiaDepartment of Neurosurgery, Capital Medical University Affiliated Beijing Tiantan Hospital, Beijing, China.
Yueping LiuDepartment of Pathology, Fourth Hospital Affiliated of Hebei Medical University, Shijiazhuang, China.
Biyun WangDepartment of Oncology, Cancer Hospital Affiliated to Fudan University, Shanghai China.ORCID https://orcid.org/0000-0001-9693-4948
Min YanDepartment of Oncology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Henan, China.
Chunfang HaoDepartment of Oncology, Tumor Hospital of Tianjin, Tianjin, China.ORCID https://orcid.org/0009-0004-8701-3687
Jiaxin ChenSenior Department of Oncology, The Fifth Medical Center of PLA General Hospital, Beijing, China.
Dan OuDepartment of Radiotherapy, Ruijin Affiliated Hospital of Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0001-6427-4199
Erwei SongSun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.ORCID https://orcid.org/0000-0002-5400-9049
Tao JiangDepartment of Neurosurgery, Capital Medical University Affiliated Beijing Tiantan Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-8529-4487
Ying MaoDepartment of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0001-8055-115X
Zefei JiangSenior Department of Oncology, The Fifth Medical Center of PLA General Hospital, Beijing, China.ORCID https://orcid.org/0009-0005-1627-1010
CSCO Expert Panel of Breast Cancer
Experts of the Neurological Tumor Specialist Committee of the Chinese Society of Clinical Oncology (CSCO)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Globally, breast cancer (BC) ranks among the most frequently diagnosed malignant tumors in women. Given the high prevalence of BC, brain metastasis (BM) arising from this malignancy are the second most frequent type among patients surpassed only by those from lung cancer. This expert consensus aims to standardize the management of BC brain metastases (BCBM) and improve patient outcomes; it serves as a practical, evidence-based guide for clinicians and allied specialists. Methods: An expert panel comprising specialists from disciplines including medical oncology, breast surgery, neurosurgery, and pathology was convened. In developing this expert consensus, the expert panel conducted a comprehensive literature review and referenced authoritative guidelines from both domestic and international sources. Results: With advancements of systemic therapies, an expanding array of medications has demonstrated efficacy against BCBM, especially among individuals with human epidermal growth factor receptor 2 (HER2)-positive BCBM. In this consensus, we systematically evaluate the following key components: clinical manifestations, imaging assessments, pathological diagnosis, treatment strategies, prognostic outcomes, follow-up and post-treatment monitoring. Conclusions: This updated consensus incorporates significant revisions across key domains-including pathological diagnosis, chemotherapy, anti-HER2 targeted therapy, and the sequencing of radiotherapy and systemic treatments-while introducing new recommendations on imaging surveillance criteria and frequency, other targeted agents, and the integration of systemic therapy with local modalities.

Indexed as

brain metastases (BMs)Breast cancer (BC)expert consensus

Identifiers

PMID42170569
PMCPMC13187562

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.