Evidence map›Paper›PMID 42170355›Full record

ReviewArrhythmia & electrophysiology review2026

Next-generation ICDs: Individualised Selection for Improved Cardiac Outcomes.

Lin-Thiri Toon, Christopher Monkhouse, Waqas Ullah, John Paisey

Abstract readReview
In one paragraph

Review in Arrhythmia & electrophysiology review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lin-Thiri ToonDepartment of Cardiology, University Hospital Southampton NHS Foundation Trust Southampton, UK.ORCID https://orcid.org/0000-0003-0805-5017
Christopher MonkhouseDepartment of Cardiology, Barts Heart Centre London, UK.ORCID https://orcid.org/0000-0002-4583-5453
Waqas UllahDepartment of Cardiology, University Hospital Southampton NHS Foundation Trust Southampton, UK.ORCID https://orcid.org/0000-0001-9317-7363
John PaiseyDepartment of Cardiology, University Hospital Southampton NHS Foundation Trust Southampton, UK.ORCID https://orcid.org/0000-0002-0220-0343

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disease is a major global cause of death, with sudden cardiac death accounting for up to half of cases, largely due to ventricular tachyarrhythmias. In the UK, approximately 60,000 out-of-hospital cardiac arrests occur annually, with survival rates of only 2-12%. Younger individuals are also affected, with one cardiac-related death daily in those under 35 years of age. Despite advances in care, arrhythmia recurrence remains high (40-50% within 5 years). ICDs have become pivotal in preventing sudden cardiac death, with continuous innovations in device design, implantation, and arrhythmia detection since their introduction in 1980. Transvenous single-chamber ICDs remain the standard, while dual-chamber and CRT defibrillator devices serve patients needing atrial pacing or heart failure support. Subcutaneous and extravascular ICD systems protect patients not requiring pacing while avoiding lead-related risks. Device selection must be individualised, considering clinical profile, comorbidities, lifestyle, patient preferences, and operator expertise. Ongoing advances, including leadless pacing and modular anti-tachycardia pacing systems, continue to expand personalised device strategies.

Indexed as

extravascular ICDICDICD selectionpersonalised therapysubcutaneous ICDtransvenous ICD

Identifiers

PMID42170355
PMCPMC13187929

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.