ArticleTranslational lung cancer research2026
Preoperative
Article in Translational lung cancer research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
7 authors.
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Abstract
Background: Methods: Data on 2,414 stage I-III NSCLC patients who underwent preoperative Results: Among 2,414 patients, 186 (7.70%) with ground-glass opacity (GGO)-predominant tumors had no MLN metastasis. Among 2,228 (92.29%) patients with solid-predominant tumors, multivariate logistic regression identified N2 lymph node enlargement on CT, pure-solid tumor and MLN maximum standard uptake value (SUVmax) as independent predictors of pN2 status. Multivariate logistic regression model based on preoperative PET/CT metrics achieved an area under the curve (AUC) of 0.7521. Conclusions: For patients presenting with GGO-predominant subsolid nodules, unnecessary PET/CT scans can be omitted to prevent over-diagnosis and excessive surgical intervention. Based on clinical characteristics of cT1 tumors, we propose a preliminary strategy for identifying patients with minimal MLN metastasis risk using PET/CT metrics, laying groundwork for prospective validation.
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