Evidence map›Paper›PMID 42170287›Full record

ReviewTranslational lung cancer research2026

Targeted therapy for stage IA non-small cell lung cancer with

Yafei Xie, Liang Xia, Zhenyi Niu, Xiaolong Zhang, Yikai Xing, Xingqi Mi, Zhangyi Dai, Guangjian Zhang, Jian Hu, Qiang Pu

Abstract readReview
In one paragraph

Review in Translational lung cancer research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yafei Xie *Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.
Liang Xia *Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.
Zhenyi NiuDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.
Xiaolong ZhangDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.
Yikai XingDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.
Xingqi MiDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.
Zhangyi DaiDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.
Guangjian ZhangDepartment of Thoracic Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Jian HuDepartment of Thoracic Surgery, The First Affiliated Hospital of Medical School of Zhejiang University, Hangzhou, China.
Qiang PuDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients with stage IA epidermal growth factor receptor ( Methods: This scoping review was conducted following PRISMA-ScR. Searches of nine literature databases and six clinical trial registries were completed on June 18, 2025. Literature selection and data extraction were performed using double-blinded and third-party arbitration methods. Findings were categorized into direct evidence, indirect evidence, and ongoing trials, visualized in tabular and graphical formats. Results: We retrieved 3,308 records. After a two-step screening process, 33 published studies and 22 ongoing clinical trials were retained. Among the 33 publications, 12 served as direct evidence sources and 21 as indirect evidence sources, all reporting potential benefits of EGFR-tyrosine kinase inhibitors (EGFR-TKIs). Publications release and clinical trials initiation were concentrated after 2020, with China as the primary country of conduct. Among the studies, first-generation erlotinib and third-generation osimertinib were the most frequently used agents. Common high-risk factors included micropapillary, solid, complex gland components (CGC), spread through air spaces (STAS), minimal residual disease (MRD), and lymphovascular invasion (LVI). Conclusions: Direct evidence for targeted therapy in patients with stage IA

Indexed as

EGFR-tyrosine kinase inhibitors (EGFR-TKIs)epidermal growth factor receptor (EGFR)non-small cell lung cancer (NSCLC)stage IATargeted therapy

Identifiers

PMID42170287
PMCPMC13186650

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.