Evidence map›Paper›PMID 42170225›Full record

ArticlemHealth2026

Evaluation of AI-generated versus registered dietitian-authored nutrition responses: a cross-sectional study.

Kathryn Ayres, Maryam Nadery, Pia Henfridsson

Abstract read
In one paragraph

Article in mHealth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kathryn AyresDepartment of Public and Allied Health, College of Health and Human Services, Bowling Green State University, Bowling Green, OH, USA.ORCID https://orcid.org/0009-0004-6671-5532
Maryam NaderyDepartment of Dietetics and Nutrition, Robert Stempel College of Public Health & Social Work, Florida International University, Miami, FL, USA.ORCID https://orcid.org/0000-0002-1855-9393
Pia HenfridssonDepartment of Dietetics and Nutrition, Robert Stempel College of Public Health & Social Work, Florida International University, Miami, FL, USA.ORCID https://orcid.org/0000-0001-7647-7997

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Artificial intelligence (AI) has emerged as a potential tool in nutrition counseling, but its performance compared with registered dietitians (RDs) remains unclear. This study aimed to compare the clinical quality, empathy, and readability of nutrition responses by a large language model (LLM, ChatGPT-4o) with those provided by licensed RDs, as assessed by RD evaluators. Methods: In this cross-sectional study, 100 nutrition-related questions were selected from public online forums where RDs had provided answers. Each question was paired with an AI-generated response. Licensed RDs (n=8), blinded to the source, rated responses for quality and empathy (5-point Likert scales) and overall performance (0-100). Readability was assessed using the Flesch Reading Ease Score (FRES), Flesch-Kincaid Grade Level (FKGL), syllables per word, and words per sentence. Statistical analyses included independent two-tailed t-tests, z-tests for proportions meeting a threshold for "acceptable" (≥4), Pearson correlations, and sensitivity analyses by response length. Results: AI-generated responses scored higher than RD-authored responses for quality (4.48±0.31 Conclusions: AI-generated nutrition responses demonstrated consistently high perceived quality and empathy, independent of length, while RD-authored responses display greater variability but higher readability. These findings highlight both the promise and the limitations of LLMs in nutrition counseling, suggesting that AI may complement, but not replace, human expertise, provided that accuracy, transparency, and professional oversight are maintained.

Indexed as

Artificial intelligence (AI)chatbotempathynutrition counselingregistered dietitian (RD)

Identifiers

PMID42170225
PMCPMC13187554

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.