Evidence map›Paper›PMID 42170092›Full record

ArticleRSC advances2026

Encapsulation of the novel mPGES-1 inhibitor TG554 in acetalated dextran nanoparticles.

Franziska Adermann, Jana Ismail, Thorben Köhler, Lea C Klepsch, Bärbel Beringer-Siemers, Carolin Kellner, Steffi Stumpf, David Pretzel, Lisa Jäpel, Ivo Nischang and 9 more

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Franziska AdermannLaboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena Humboldtstraße 10 07743 Jena Germany ulrich.schubert@uni-jena.de.ORCID https://orcid.org/0009-0003-4012-7567
Jana IsmailLaboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena Humboldtstraße 10 07743 Jena Germany ulrich.schubert@uni-jena.de.ORCID https://orcid.org/0000-0002-8475-5683
Thorben KöhlerLaboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena Humboldtstraße 10 07743 Jena Germany ulrich.schubert@uni-jena.de.ORCID https://orcid.org/0009-0002-4912-5747
Lea C KlepschLaboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena Humboldtstraße 10 07743 Jena Germany ulrich.schubert@uni-jena.de.ORCID https://orcid.org/0009-0009-3849-1670
Bärbel Beringer-SiemersLaboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena Humboldtstraße 10 07743 Jena Germany ulrich.schubert@uni-jena.de.
Carolin KellnerLaboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena Humboldtstraße 10 07743 Jena Germany ulrich.schubert@uni-jena.de.
Steffi StumpfLaboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena Humboldtstraße 10 07743 Jena Germany ulrich.schubert@uni-jena.de.
David PretzelLaboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena Humboldtstraße 10 07743 Jena Germany ulrich.schubert@uni-jena.de.
Lisa JäpelLaboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena Humboldtstraße 10 07743 Jena Germany ulrich.schubert@uni-jena.de.
Ivo NischangLaboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena Humboldtstraße 10 07743 Jena Germany ulrich.schubert@uni-jena.de.ORCID https://orcid.org/0000-0001-6182-5215
Zehra Tuğçe Gür MazDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Gazi University 06560 Ankara Turkey.
Philipp DahlkeDepartment of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena Philosophenweg 14 07743 Jena Germany.
Hannes EngelbrechtDepartment of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena Philosophenweg 14 07743 Jena Germany.ORCID https://orcid.org/0009-0003-9446-8666
Paul M JordanJena Center for Soft Matter (JCSM), Friedrich Schiller University Jena Philosophenweg 7 07743 Jena Germany.ORCID https://orcid.org/0000-0002-8364-4236
Antje VollrathLaboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena Humboldtstraße 10 07743 Jena Germany ulrich.schubert@uni-jena.de.ORCID https://orcid.org/0000-0001-5801-7743
Stephanie SchubertLaboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena Humboldtstraße 10 07743 Jena Germany ulrich.schubert@uni-jena.de.ORCID https://orcid.org/0000-0001-9527-7763
Erden BanogluDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Gazi University 06560 Ankara Turkey.
Oliver WerzJena Center for Soft Matter (JCSM), Friedrich Schiller University Jena Philosophenweg 7 07743 Jena Germany.
Ulrich S SchubertLaboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena Humboldtstraße 10 07743 Jena Germany ulrich.schubert@uni-jena.de.ORCID https://orcid.org/0000-0003-4978-4670

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic inflammatory conditions remain a major therapeutic challenge, driving the demand for more selective and well-tolerated treatment options. The 2-amino-1,3,4-oxadiazole-based TG554, a novel and highly potent inhibitor of microsomal prostaglandin E

Identifiers

PMID42170092
PMCPMC13187903

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.