Evidence map›Paper›PMID 42170048›Full record

ArticleAJOG global reports2026

Ultrasound-guided radiofrequency ablation of an intramural fibroid in a woman desiring fertility with coexisting focal adenomyosis: a case report.

Francesco G Martire, Claudia d'Abate, Eugenia Costantini, Ilaria Ianes, Emilio Pieri, Lorenza Minisci, Maria De Bonis, Lucia Lazzeri, Errico Zupi

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in AJOG global reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Francesco G MartireDepartment of Molecular and Developmental Medicine, Obstetrics and Gynecological Clinic, University of Siena, Siena, Italy.
Claudia d'AbateDepartment of Molecular and Developmental Medicine, Obstetrics and Gynecological Clinic, University of Siena, Siena, Italy.
Eugenia CostantiniDepartment of Molecular and Developmental Medicine, Obstetrics and Gynecological Clinic, University of Siena, Siena, Italy.
Ilaria IanesDepartment of Molecular and Developmental Medicine, Obstetrics and Gynecological Clinic, University of Siena, Siena, Italy.
Emilio PieriDepartment of Molecular and Developmental Medicine, Obstetrics and Gynecological Clinic, University of Siena, Siena, Italy.
Lorenza MinisciDepartment of Molecular and Developmental Medicine, Obstetrics and Gynecological Clinic, University of Siena, Siena, Italy.
Maria De BonisDepartment of Molecular and Developmental Medicine, Obstetrics and Gynecological Clinic, University of Siena, Siena, Italy.
Lucia LazzeriDepartment of Molecular and Developmental Medicine, Obstetrics and Gynecological Clinic, University of Siena, Siena, Italy.
Errico ZupiDepartment of Molecular and Developmental Medicine, Obstetrics and Gynecological Clinic, University of Siena, Siena, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To report the reproductive outcome after ultrasound-guided radiofrequency ablation (RFA) in a woman with an intramural uterine fibroid and coexisting focal adenomyosis who experienced infertility and desired pregnancy. Design: Case report. Patient: A 40-year-old nulligravid woman with heavy menstrual bleeding, dysmenorrhea, and a history of infertility, defined by failure to conceive after more than 12 months of unprotected intercourse. Transvaginal ultrasound demonstrated a FIGO type 3 intramural fibroid distorting the endometrial cavity and associated focal anterior adenomyosis. Intervention: Ultrasound-guided transvaginal RFA of the intramural fibroid. Main Outcome Measures: Changes in fibroid volume and uterine cavity morphology on ultrasound, improvement of clinical symptoms, and reproductive outcome. Results: The procedure was completed without complications. Follow-up ultrasound showed progressive fibroid volume reduction of 76.9% at 6 months, migration of the lesion away from the endometrial cavity, restoration of normal cavity anatomy, and improvement of sonographic features of focal adenomyosis. Menstrual symptoms improved significantly. Spontaneous conception subsequently occurred, resulting in an uncomplicated term vaginal delivery. Conclusion: This case suggests that ultrasound-guided RFA may represent a minimally invasive, uterus-sparing option for selected women with intramural fibroids and coexisting focal adenomyosis associated with infertility.

Indexed as

adenomyosisfertility preservationradiofrequency ablationtransvaginalultrasonographyuterine fibroids

Identifiers

PMID42170048
PMCPMC13188077

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.