ArticleJournal of gastrointestinal oncology2026
Molecular characteristics and metastatic mechanism of patients diagnosed with Krukenberg tumor from gastric cancer.
Article in Journal of gastrointestinal oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
11 authors.
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Abstract
Background: Krukenberg tumors (KTs) represent a distinct form of ovarian metastasis originating from gastric cancer (GC) and are associated with dismal clinical outcomes. Despite their clinical significance, the molecular landscape and underlying mechanisms driving KTs development remain largely undefined. Our goal was to delineate the molecular landscape and metastatic evolutionary pattern of KTs, thereby informing the development of therapeutic strategies. Methods: We conducted whole-exome sequencing (WES) on paired primary gastric and metastatic ovarian tumors from 11 patients with KTs in a retrospective cohort. Results: Conclusions: Frequent
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