ArticleJournal of gastrointestinal oncology2026
The prevalence of gastric intestinal metaplasia in the Saudi population: a single-tertiary center retrospective study.
Article in Journal of gastrointestinal oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Gastric intestinal metaplasia (GIM) is characterized by the transformation of gastric mucosa into an intestinal phenotype. This condition arises from gastric cell inflammation caused by various etiologies, such as infection or autoimmune reactions. GIM is a critical stage in the carcinogenic pathway and may progress into gastric cancer (GC), one of the most prevalent and morbid cancers worldwide. In this study, we examined the prevalence of GIM among patients who underwent upper endoscopy or gastric resection, along with associated risk factors. Methods: This retrospective study included 2,103 patients who underwent upper endoscopy or gastric resection at a tertiary facility. Data on patient demographics, risk factors, procedural indications and tissue sampling were collected and analyzed. Results: GIM was identified in 119 patients (5.7%) who had significantly higher mean age (55.83±15.88 years, P value <0.001) compared to the non-GIM group. Among all patients, 547 had Conclusions: A significantly higher proportion of patients with GIM had coexisting GC and dysplasia. Advanced age and
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