Evidence map›Paper›PMID 42169815›Full record

ArticleCase reports in critical care2026

Management of an Autism Spectrum Disorder (ASD) Patient With Respiratory Failure in the Intensive Care Unit: A Case Report on the Role of Dexmedetomidine.

Alessandra Ciccozzi, Federico Murgia, Alba Piroli, Antonella Paladini, Claudia Ciccone, Francesca Leonardis, Davide Fionda, Antonello Ciccone, Franco Marinangeli

Abstract read
In one paragraph

Article in Case reports in critical care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alessandra CiccozziDepartment of Life, Health and Environmental Sciences-University of L'Aquila, L'Aquila, Italy.ORCID https://orcid.org/0000-0003-0250-7991
Federico MurgiaDepartment of Life, Health and Environmental Sciences-University of L'Aquila, L'Aquila, Italy.ORCID https://orcid.org/0009-0009-1946-6402
Alba PiroliDepartment of Life, Health and Environmental Sciences-University of L'Aquila, L'Aquila, Italy.ORCID https://orcid.org/0000-0002-1722-6490
Antonella PaladiniDepartment of Life, Health and Environmental Sciences-University of L'Aquila, L'Aquila, Italy.ORCID https://orcid.org/0000-0002-1219-9315
Claudia CicconeDepartment of Surgical Sciences, Hospital-University Company City of Health and Science of Turin, Università degli Studi di Torino Dipartimento di Scienze Chirurgiche, Turin, Italy.ORCID https://orcid.org/0009-0004-3809-5698
Francesca LeonardisIntensive Care Unit, Tor Vergata University Hospital, Università degli Studi di Roma Tor Vergata Facoltà di Medicina e Chirurgia, Rome, Italy, uniroma2.it.ORCID https://orcid.org/0000-0003-2523-5706
Davide FiondaDepartment of Anaesthesia and Intensive Care, Ospedale Civile San Salvatore, University Hospital of L'Aquila, L'Aquila, Italy.ORCID https://orcid.org/0009-0009-7594-2047
Antonello CicconeDepartment of Anaesthesia and Intensive Care, Ospedale Civile San Salvatore, University Hospital of L'Aquila, L'Aquila, Italy.ORCID https://orcid.org/0009-0002-2454-9834
Franco MarinangeliDepartment of Life, Health and Environmental Sciences-University of L'Aquila, L'Aquila, Italy.ORCID https://orcid.org/0000-0002-4931-7717

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This clinical case describes the management, in an intensive care unit (ICU), of a patient with a severe form of autism spectrum disorder (ASD) Level 3, suffering from acute respiratory failure that evolved into acute respiratory distress syndrome (ARDS). Throughout the entire period of hospitalisation in the ICU, sedation of the patient played a key role in the performance of all invasive and noninvasive therapeutic procedures, in particular artificial ventilation and subsequent weaning, due to the underlying disorder that rendered the patient completely uncooperative. Dexmedetomidine was used during initial admission to the ICU for initial treatment, during the period of artificial ventilation and finally during weaning from mechanical ventilation. The

Indexed as

autism spectrum disorderdexmedetomidinerespiratory failuresedationspecial needs

Identifiers

PMID42169815
PMCPMC13189493

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.