Evidence map›Paper›PMID 42169764›Full record

ArticleJournal of human immunity2025

Immunotherapy as rescue for cardiomyopathy in Omenn syndrome.

Simon Boutinaud, Vincent Barlogis, Lionel Berthomieu, Montserrat Sierra Colomina, Marlène Pasquet

Abstract read
In one paragraph

Article in Journal of human immunity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Simon BoutinaudDepartment of Pediatric Immunology, CHU Toulouse, Toulouse, France.ORCID https://orcid.org/0009-0006-0413-0613
Vincent BarlogisDepartment of Pediatric Immunology, Assistance publique - Hôpitaux de Marseille, Marseille, France.ORCID https://orcid.org/0000-0001-9645-3968
Lionel BerthomieuDepartment of Pediatric Critical Care, CHU Toulouse, Toulouse, France.ORCID https://orcid.org/0009-0005-5661-5965
Montserrat Sierra ColominaDepartment of Pediatric Critical Care, CHU Toulouse, Toulouse, France.ORCID https://orcid.org/0000-0001-5714-9357
Marlène PasquetDepartment of Pediatric Immunology, CHU Toulouse, Toulouse, France.ORCID https://orcid.org/0000-0001-6919-8383

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 6-month-old infant with Omenn syndrome and severe hypertrophic cardiomyopathy showed significant clinical improvement following multimodal immunosuppression with anti-IL-5 and alemtuzumab. This targeted approach successfully stabilized the patient, providing a critical bridge to curative hematopoietic stem cell transplantation.

Identifiers

PMID42169764
PMCPMC13177394

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.