Evidence map›Paper›PMID 42169593›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2026

Adherence to Helicobacter pylori Management Consensus in Clinical Practice at Two Tertiary Hospitals: A Large Cohort Study.

Pudit Chinniyomwanich, Puth Muangpaisarn, Rapat Pittayanon

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Article in Asian Pacific journal of cancer prevention : APJCP, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Pudit ChinniyomwanichDepartment of Internal Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.ORCID 0009-0003-6937-8327
Puth MuangpaisarnDivision of Gastroenterology, Department of Internal Medicine, Phrapokklao Hospital, Chanthaburi, Thailand.
Rapat PittayanonDepartment of Internal Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.ORCID 0000-0001-6407-5245

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany countries have launched Helicobacter pylori (HP) management guidelines to assist physicians, based on regional data. However, adherence is often assessed using questionnaires, which may not accurately reflect real-world practice. This study aimed to assess adherence to the Thailand Consensus on HP management through a retrospective chart review conducted at two tertiary hospitals in Thailand. MATERIALS AND

methodsThis retrospective study was conducted at King Chulalongkorn Memorial Hospital (KCMH), located in the capital, and Phrapokklao Hospital (PPK), located in a province. Medical records of patients diagnosed with Helicobacter pylori (HP) infection via esophagogastroduodenoscopy (EGD) with a rapid urease test (RUT) between 2019 and 2021 were reviewed. Collected data included demographics, indications for HP testing, pre-EGD preparation, treatment regimens, and follow-up practices.

results2,136 medical records were reviewed: 1,987 KCMH and 149 PPK. Most patients were Thai under universal health coverage. Pre-diagnostic preparation at KCMH showed 98.5% discontinued proton pump inhibitors (PPIs) ≥2 weeks, compared to 83.9% at PPK (p < 0.001). Antibiotic discontinuation ≥4 weeks was higher at KCMH (98.6% vs 95.3%, p = 0.009). For first-line, KCMH (74.6%) received PPI-based triple therapy for 14 days, while 77.5% at PPK received concomitant therapy. 78% at KCMH confirmed HP eradicate vs 44.1% at PPK (p < 0.001). Eradication rates were comparable (95.9% at PPK vs 89.4% at KCMH: p = 0.139).

conclusionThis study highlights suboptimal adherence to the Helicobacter pylori (HP) consensus in provincial hospitals in Thailand, suggesting that future guidelines should address healthcare limitations outside the capital to enhance the overall quality of national healthcare.

Indexed as

Anti-Bacterial AgentsGuideline AdherenceHelicobacter InfectionsHelicobacter pyloriPractice Guidelines as TopicPractice Patterns, Physicians'ConsensusFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisProton Pump InhibitorsRetrospective StudiesTertiary Care CentersAnti-Bacterial AgentsProton Pump InhibitorsAdherenceClinical GuidelinesHelicobacter pyloriReal-world practice

Identifiers

PMID42169593
PMCPMC13652286

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.