Evidence map›Paper›PMID 42169582›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2026

Detection of Stages of Oral Cavity Lesions Using a Fluorescence Portable Device and Their Classification by Artificial Intelligence Tools.

Pavan Kumar, Amar Nath Sah, Vikrant Yashwant Ganvir, Asima Pradhan, Roshni Rathour

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Article in Asian Pacific journal of cancer prevention : APJCP, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Pavan KumarFaculty of Engineering and Technology (FEAT), Datta Meghe Institute of Higher Education and Research (DMIHER), Wardha 442001, India.ORCID 0000-0001-6845-9959
Amar Nath SahCentre for Quantum Science and Technology, Sikha 'O' Anusandhan (SOA), Jagamara, Bhubaneswar, India.
Vikrant Yashwant GanvirDepartment of Applied Physics, Yeshwantrao Chavan College of Engineering (YCCE), Nagpur, India.
Asima PradhanSikha 'O' Anusandhan (SOA), Jagamara, Bhubaneswar, India.
Roshni RathourDepartment of CSE, Yeshwantrao Chavan College of Engineering (YCCE), Nagpur, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn the present study, we utilized a fluorescence-based portable device for the detection of oral lesions, as well as AI tools for the classification of the spectroscopic data. The portable device comprises optical components (lens, filters, and beam splitter), a laser, a spectrometer, and other accessories (laptop, fibers, etc.). Laser light (λexc= 405 nm), irradiated onto the lateral border of the tongue (LBT) of the oral cavity tissue, excites the fluorophores FAD (λemi ≈ 500 nm) and Porphyrin (λemi ≈ 634 nm) more significantly than the others.

methodsFluorescence spectra were recorded from three groups, i.e., OSCC, Dysplastic, and Normal, in the range of 450 to 750 nm. Among these groups, OSCC and Dysplastic patients exhibited a significant rise in porphyrin fluorescence.

resultData analysis was accomplished using AI tools, namely Principal Component Analysis (PCA), K-Nearest Neighbors (KNN), Naïve Bayes, Linear and Quadratic Discriminant Analysis (LDA & QDA), and ROC analysis. Among these AI tools, the PCA-based QDA classifier was capable of discerning among the groups with slightly higher accuracy values (≈ 98%) than the other AI tools.

conclusionResults reveal that the in-house-built fluorescence device, along with QDA, would be an elegant tool for the identification of oral lesions at the preliminary stage.

Indexed as

Artificial IntelligenceMouth NeoplasmsFluorescenceHumansPrincipal Component AnalysisPrognosisSpectrometry, FluorescenceArtificial intelligenceFluorescenceoral lesionsporphyrin

Identifiers

PMID42169582
PMCPMC13652092

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