Evidence map›Paper›PMID 42169450›Full record

Trial reportPhysiological reports2026

Short-term effects of weight-loading on heart rate variability in obese adults.

Jakob Bellman, Per-Anders Jansson, John-Olov Jansson, Claes Ohlsson, Lennart Bergfeldt

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Physiological reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jakob BellmanDepartment of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0002-9616-3407
Per-Anders JanssonRegion Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden.
John-Olov JanssonDepartment of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Claes OhlssonSahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Lennart BergfeldtWallenberg Laboratory, Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0002-0161-9388

Funding

Göteborgs Läkaresällskap (Göteborg Medical Society) GLS-1020343Knut och Alice Wallenbergs Stiftelse (Knut and Alice Wallenberg Foundation) KAW 2020.0230Stiftelsen Längmanska Kulturfonden BA25-2101Stiftelsen Lars Hiertas Minne (Lars Hierta Memorial Foundation) FO2024-0310Stiftelsen Mary von Sydows, född Wijk, donationsfond (Mary von Sydow Foundation) 2024-139Västra Götalandsregionen (Region Västra Götaland) ALFGBG-965051Västra Götalandsregionen (Region Västra Götaland) ALFGBG-979083
6 · The paper itself

Abstract

Weight-loading reduces body fat, but its effects on cardiac autonomic modulation remain unclear. We examined heart rate variability (HRV) during free-living weight-loading in adults with class I obesity. Fifty-one participants (27 females) were randomized to wear a heavy (11% of body weight) or a light vest (1%) for 8 h/day for 15 days. Twenty-four-hour ECG recordings were obtained before and on day 15. Heart rate (HR), relative HR reserve (%HRR), and time- and frequency-domain HRV indices were analyzed across four predefined periods: morning (rest), afternoon (vest-usage), evening, and night. During the afternoon period, the high versus low load increased HR (p = 0.0496) and %HRR (p = 0.03), while reducing SDNN (standard deviation of normal-to-normal intervals; p = 0.01) and RMSSD (root mean square of successive differences; p = 0.002). In females, but not in males, high load was associated with lower high-frequency power (P

Indexed as

Heart RateObesityWeight-BearingAdultAutonomic Nervous SystemElectrocardiographyFemaleHumansMaleautonomic modulationautonomic nervous systemheart rate variabilityobesityphysical activityweight‐loading

Identifiers

PMID42169450
PMCPMC13239273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.