Evidence map›Paper›PMID 42169438›Full record

ArticleThe New phytologist2026

AI-designed OpenCRISPR-1 performs robust knockout, base editing, and prime editing in rice.

Priya Das, Romio Saha, Debasmita Panda, Chandana Ghosh, S P Avinash, Sonali Panda, Mirza J Baig, Kutubuddin A Molla

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The New phytologist, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Priya Das *ICAR-Central Rice Research Institute, Cuttack, 753006, India.ORCID https://orcid.org/0009-0003-3539-4038
Romio Saha *ICAR-Central Rice Research Institute, Cuttack, 753006, India.ORCID https://orcid.org/0009-0003-7455-6298
Debasmita PandaICAR-Central Rice Research Institute, Cuttack, 753006, India.
Chandana GhoshICAR-Central Rice Research Institute, Cuttack, 753006, India.
S P AvinashICAR-Central Rice Research Institute, Cuttack, 753006, India.ORCID https://orcid.org/0000-0002-5820-4343
Sonali PandaICAR-Central Rice Research Institute, Cuttack, 753006, India.ORCID https://orcid.org/0009-0002-2503-9545
Mirza J BaigICAR-Central Rice Research Institute, Cuttack, 753006, India.
Kutubuddin A MollaICAR-Central Rice Research Institute, Cuttack, 753006, India.ORCID https://orcid.org/0000-0002-9897-7906

Funding

Department of Biotechnology, Ministry of Science and Technology, India BT/PR53972/PBN/18/25/2024Department of Biotechnology, Ministry of Science and Technology, India IC-12048(12)/4/2024-MED-DBTIgnite Life Science Foundation Projects/AgSci/22-23/01Indian Council of Agricultural Research
6 · The paper itself

Abstract

Plant OpenCRISPR-1 (POC1) mediates knockout and adenine base editing in rice.

Indexed as

Gene EditingGene Knockout TechniquesOryzaBase SequencePlants, Genetically ModifiedRNA Editingartificial intelligence (AI)‐designed nucleasebase editingCas9 alternativeprime editingrice genome editingtracrRNA

Identifiers

PMID42169438
PMCPMC13443147

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.