Evidence map›Paper›PMID 42169184›Full record

ArticleVeterinary research2026

Potent neutralization and therapeutic efficacy of bovine rotavirus-specific VHH antibodies in infected calves.

Qihuan Zhao, Min Gao, Puchen Li, Bo Wang, Baohui Li, Gege Rile, Chengquan Du, Jingjing Wang, Hui Wang, Jingsi Mei and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Qihuan Zhao *College of Veterinary Medicine, Inner Mongolia Agricultural University, No. 306, Zhaowuda Road, Saihan District, Huhhot, 010018, China.
Min Gao *Fisheries Technology Division, Inner Mongolia Autonomous Region Agricultural and Animal Husbandry Technology Promotion Center, Huhhot, 010010, China.
Puchen LiWuyuan County Animal Disease Prevention and Control Center, Bayannur, 015100, China.
Bo WangCollege of Veterinary Medicine, Inner Mongolia Agricultural University, No. 306, Zhaowuda Road, Saihan District, Huhhot, 010018, China.
Baohui LiCollege of Veterinary Medicine, Inner Mongolia Agricultural University, No. 306, Zhaowuda Road, Saihan District, Huhhot, 010018, China.
Gege RileCollege of Veterinary Medicine, Inner Mongolia Agricultural University, No. 306, Zhaowuda Road, Saihan District, Huhhot, 010018, China.
Chengquan DuCollege of Veterinary Medicine, Inner Mongolia Agricultural University, No. 306, Zhaowuda Road, Saihan District, Huhhot, 010018, China.
Jingjing WangCollege of Veterinary Medicine, Inner Mongolia Agricultural University, No. 306, Zhaowuda Road, Saihan District, Huhhot, 010018, China.
Hui WangCollege of Veterinary Medicine, Inner Mongolia Agricultural University, No. 306, Zhaowuda Road, Saihan District, Huhhot, 010018, China.
Jingsi MeiCollege of Veterinary Medicine, Inner Mongolia Agricultural University, No. 306, Zhaowuda Road, Saihan District, Huhhot, 010018, China.
Shujun ZhangCollege of Veterinary Medicine, Inner Mongolia Agricultural University, No. 306, Zhaowuda Road, Saihan District, Huhhot, 010018, China. zhangshujun@imau.edu.cn.
Fuxiang BaoCollege of Veterinary Medicine, Inner Mongolia Agricultural University, No. 306, Zhaowuda Road, Saihan District, Huhhot, 010018, China. baofuxiang@imau.edu.cn.

Funding

Basic Scientific Research Fund of Directly Affiliated Universities in Inner Mongolia Autonomous Region BR250101National Natural Science Foundation of China 32260893Natural Science Foundation of Inner Mongolia Autonomous Region 2022MS03019Program for Young Talents of Science and Technology in Universities of the Inner Mongolia Autonomous Region NJYT23094Science and Technology Major Project of Inner Mongolia Autonomous Region of China 2023YFXZ0002
6 · The paper itself

Abstract

Bovine rotavirus is one of the main pathogens causing acute diarrhea in calves under 1 month of age, posing a serious threat to intensive cattle farming, and there are no effective therapeutic agents owing to the mixed infection of bovine rotavirus (BRV) with other pathogens. In this study, we successfully constructed a phage display antibody library by immunizing Bactrian camels, with a capacity of 6.5 × 10

Indexed as

Antibodies, NeutralizingAntibodies, ViralCattle DiseasesRotavirusRotavirus InfectionsSingle-Domain AntibodiesAnimalsCamelusCattleEnzyme-Linked Immunosorbent AssayNeutralization TestsAntibodies, NeutralizingAntibodies, ViralSingle-Domain AntibodiesBovine rotavirussingle-domain antibodiestreatment

Identifiers

PMID42169184
PMCPMC13195868

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.