Evidence map›Paper›PMID 42169158›Full record

ArticleSystematic reviews2026

Reviewing ecosystems of evidence: synthesising the evidence on the commercial determinants of health from a complex systems perspective.

Alice Tompson, James Thomas, Harry Rutter, Laurence Blanchard, Éadaoin Cott, Rebecca E Glover, Cecile Knai, Nason Maani, May C I van Schalkwyk, Vivian Welch and 1 more

Abstract read
In one paragraph

Article in Systematic reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alice TompsonDepartment of Public Health, Environments and Society, Faculty of Public Health and Policy, LSHTM, London, UK. alice.tompson@lshtm.ac.uk.ORCID 0009-0000-6192-1362
James ThomasEPPI-Centre, Social Science Research Unit, UCL Institute of Education, University College London, London, UK.
Harry RutterCentre for 21st Century Public Health, University of Bath, Bath, UK.
Laurence BlanchardDepartment of Health Services Research and Policy, Faculty of Public Health and Policy, LSHTM, London, UK.
Éadaoin CottDepartment of Health, University of Bath, Bath, UK.
Rebecca E GloverDepartment of Public Health, Environments and Society, Faculty of Public Health and Policy, LSHTM, London, UK.
Cecile KnaiDepartment of Health Services Research and Policy, Faculty of Public Health and Policy, LSHTM, London, UK.
Nason MaaniGlobal Health Policy Unit, School of Social and Political Science, The University of Edinburgh, Edinburgh, UK.
May C I van SchalkwykGlobal Health Policy Unit, School of Social and Political Science, The University of Edinburgh, Edinburgh, UK.
Vivian WelchBruyère Research Institute, University of Ottawa, Ottawa, Canada.
Mark PetticrewDepartment of Public Health, Environments and Society, Faculty of Public Health and Policy, LSHTM, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Commercial Determinants of Health (CDoH) are the systems, practices, and pathways through which commercial actors drive health and equity. This includes their influence on systems of evidence production and dissemination (evidence ecosystems) in order to protect and promote commercial interests. In the Commercial Determinants of Health and Evidence Synthesis (CODES) methodological guidance, we provided advice for conducing CDoH relevant evidence syntheses, from developing a protocol to reporting the review and planning an update. This follow-up paper considers reasons and practical implications for integrating a complex systems perspective in such reviews. This commentary describes how a complex systems perspective can benefit research, including evidence synthesis related to the CDoH, by embracing the complexity of the real world, understanding interventions in context, rendering visible the corporate playbook, and exposing the power dynamics that drive inequity. We then reflect on the practical implications of adopting a complex systems approach in CDoH evidence synthesis, including drawing on a systems lens and/or incorporating specific systems methods in the review. This commentary complements existing CODES guidance in highlighting considerations for conducting CDoH relevant evidence synthesis from a complex systems perspective. It can help interpreting such reviews and raise awareness of how commercial actors can shape evidence ecosystems, particularly evidence synthesis. Having a robust evidence base that considers systems elements and dynamics will support effective action to address the CDoH, improve public health and reduce inequity at scale.

Indexed as

CommerceSocial Determinants of HealthEcosystemHumansCommercial determinants of healthComplex systemsMethodsSystematic reviewsSystems thinking

Identifiers

PMID42169158
PMCPMC13195904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.