Evidence map›Paper›PMID 42168974›Full record

ArticleBMC pediatrics2026

Epidemiology of children and adolescents undergoing surgery at Mexican public hospitals: a retrospective registry-based analysis from 2010 to 2022.

Magdalena Gruendl, Letícia Nunes Campos, Tanujit Dey, Theoneste Nkurunziza, Taylor Wurdeman, Gunther Schauberger, Arturo Cervantes Trejo, Jaime Shalkow-Klincovstein, Stefanie J Klug, Tarsicio Uribe-Leitz

Abstract read
In one paragraph

Article in BMC pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Magdalena GruendlChair of Epidemiology, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany. magdalena.gruendl@tum.de.
Letícia Nunes CamposProgram in Global Surgery and Social Change, Harvard Medical School, Boston, USA.
Tanujit DeyThe Center for Surgery and Public Health, Brigham and Women's Hospital, Boston, USA.
Theoneste NkurunzizaChair of Epidemiology, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany.
Taylor WurdemanProgram in Global Surgery and Social Change, Harvard Medical School, Boston, USA.
Gunther SchaubergerChair of Epidemiology, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany.
Arturo Cervantes TrejoFaculty of Health Sciences, Anahuac University, Anahuac, Mexico.
Jaime Shalkow-KlincovsteinFaculty of Health Sciences, Anahuac University, Anahuac, Mexico.
Stefanie J Klug *Chair of Epidemiology, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany.
Tarsicio Uribe-Leitz *Chair of Epidemiology, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSurgical care is essential for addressing acute and chronic conditions in children and adolescents. While national-level data on pediatric surgical procedures in Mexico exist, analysis of such data remain limited. This study aimed to describe geographic variations and temporal trends in pediatric surgical procedures performed at public hospitals from 2010 to 2022, including the impact of the COVID-19 pandemic, and to identify factors associated with in-hospital mortality.

methodsThis retrospective registry-based analysis used hospital discharge data from Mexico's Ministry of Health (MoH) public hospitals (2010-2022), including all elective and emergency surgical procedures in patients aged 0-17. Descriptive statistics summarized demographic and clinical characteristics. Surgical specialties stratified by age and sex were visualized using sankey flow diagrams. Age-standardized incidence rates (ASIR) were calculated per 100,000 children and adolescents by state and year using the WHO world standard population. Interrupted time series (ITS) analysis with Poisson regression evaluated trends of surgical procedure volume. Logistic regression identified factors associated with in-hospital mortality.

resultsAmong 752,654 pediatric surgical patients, 58.2% were male and 41.8% female. The most common age group was 10-14 years (27.7%). Overall, 42.4% were normal weight, 16.6% of patients were underweight, 21.6% overweight, 19.4% obese. Additionally, 2.1% identified as indigenous. General surgery (46.8%) and orthopedic surgery (23.4%) were the most frequent surgical procedures. The ASIR of surgical procedures was 141.8 per 100,000 children and adolescents nationwide (2010-2022). Guanajuato reported the highest overall ASIR (333.8 per 100,000), while Nuevo León had the lowest (18.5 per 100,000). Surgical procedure volumes increased until 2015, declined thereafter, and dropped sharply by 35.0% in April 2020 at the onset of the nationwide lockdown (exp(β): 0.65, 95% CI: 0.59-0.70), with volumes gradually recovering by 2022. Hospital-acquired infections (HAIs) (aOR: 2.71, 95% CI: 2.46-2.98) and prolonged length of stay (LOS) (aOR: 2.27, 95% CI: 2.13-2.41) were associated with increased in-hospital mortality.

conclusionThis national analysis demonstrates pronounced geographic and temporal disparities in pediatric surgical care across Mexico's public hospitals, including substantial declines during the COVID-19 pandemic. Coordinated investments in pediatric surgical infrastructure, state-level health information systems, and referral networks are critical to ensuring equitable, evidence-based pediatric surgical services.

Indexed as

COVID-19Hospitals, PublicSurgical Procedures, OperativeAdolescentChildChild, PreschoolFemaleHospital MortalityHumansIncidenceInfantInfant, NewbornMaleMexicoRegistriesRetrospective StudiesChildren and adolescentsEpidemiological data analysisMexicoPediatric surgerySurgical epidemiology

Identifiers

PMID42168974
PMCPMC13251272

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.