Evidence map›Paper›PMID 42168959›Full record

ArticleBMC surgery2026

Comprehensive use of combined surgical techniques performing liposuction, round-block periareolar de-epithelialization, and complete subcutaneous breast tissue resection approach in grade III gynecomastia: a review of 82 patients.

Hedieh Soltani, Zahra Nikeghbalian, Alireza Eskandari, Mojtaba Ahmadinejad, Sahar Dalvand, Sajad Karimi, Nima Amadeh, Farid Moradian

Abstract read
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Article in BMC surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Hedieh SoltaniSchool of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Zahra NikeghbalianSleep Breathing Disorders Research Center, School of Medicine, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Alireza EskandariSchool of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Mojtaba AhmadinejadDepartment of General Surgery, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Sahar DalvandDepartment of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Sajad KarimiSurgical Technologist, Niyavaran Limited Surgical Center, Tehran, Iran.
Nima AmadehSurgical Technologist, Niyavaran Limited Surgical Center, Tehran, Iran.
Farid MoradianDepartment of General Surgery, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran. Moradian.farid@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGynecomastia is associated with significant psychological and cosmetic concerns.

objectiveSurgical approaches for gynecomastia that are minimally invasive, associated with few complications, allow for rapid recovery, and result in high patient satisfaction are highly valuable. This study aims to evaluate the aesthetic efficacy and complications of accumulated techniques for treating patients with grade III gynecomastia.

methodsThe preferred strategy includes a combination of enhanced liposuction, round-block de-epithelialization, complete subcutaneous dissection of fibroglandular tissue, and reconstruction methods. Demographic characteristics, complications, satisfaction questionnaires with a 5-point Likert scale, and postoperative quality of life with WHO-QOL-BREF questionnaire were evaluated during follow-up.

resultsThis study included 82 male patients with gynecomastia grade III (including 3 transgender patients) with a mean age of 30.18 ± 7.60 and the mean BMI of 30.97 ± 3.96. The overall postoperative satisfaction of the patients was 78%. Most patients reported being satisfied or very satisfied with the breast appearance (65.8%), symmetry (75.6%), skin tightness (73.2%), excessive skin resection (64.6%), healing of the incision (62.2%), and contour irregularity (75.6%). Seroma (12.2%), and edema (31.7%) were the most reported postoperative complications which gradually resolved, whereas other complications were insignificant such as bleeding (2.4%), subcutaneous hematoma (3.7%), NAC necrosis (3.7%), and infection (2.4%). No evidence of hemo/pneumothorax, intrathoracic organ damage, and fat embolism, were observed. Regarding scar characteristics, 1.2% had prominent scars and 86.6% had small or hidden scars. Regarding incision characteristics, wound disruption occurred in 8.5% of the cases, whereas 89% of the patients had minimal and good length incisions.

conclusionEnhanced liposuction, round-block periareolar de-epithelialization, and complete subcutaneous breast tissue resection approach in patients with grade III gynecomastia and severe ptosis is a feasible, and safe approach with rapid recovery, hidden scars and acceptable patient satisfaction.

trial registrationNot applicable. This study is a retrospective observational case series and does not require trial registration.

Indexed as

GynecomastiaLipectomyMammaplastyAdultHumansMalePatient SatisfactionPostoperative ComplicationsQuality of LifeRetrospective StudiesTreatment OutcomeYoung AdultGrade IIIGynecomastiaLiposuctionPtosisRound-block de-epithelializationSubcutaneous breast tissue resection

Identifiers

PMID42168959
PMCPMC13471610

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.