ReviewAdvances in experimental medicine and biology2026
Membrane Merger Dynamics in Exocytosis and Endocytosis.
Review in Advances in experimental medicine and biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Exocytosis releases vesicular cargo to the extracellular space and adds membrane to the cell surface, whereas endocytosis retrieves membrane and internalizes extracellular material; together, they maintain membrane homeostasis and enable rapid intercellular signaling. Super-resolution imaging has revealed that these processes are far richer than the classical "kiss-and-run vs. full-collapse" or flat-to-round schemes. Exocytosis now encompasses at least seven fusion modes with reversible pores, vesicle shrinking or enlargement, and compound or sequential compound fusion, while endocytosis proceeds mainly via modular flat→Λ→Ω→O transitions and rapid closure of preformed Ω-profiles. These dynamic transformations are orchestrated by Soluble N-ethylmaleimide-sensitive factor Attachment protein REceptors, Ca
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