Evidence map›Paper›PMID 42168716›Full record

ArticlePediatric surgery international2026

Peritoneal drainage in spontaneous intestinal perforation: a 20-year single center review.

Goeto Dantes, Olivia Keane, Isabella Amaniera, Morgan Buchanan, Zhulin He, Hanna Alemayehu, Amina M Bhatia

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Article in Pediatric surgery international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Goeto DantesDepartment of Surgery, Emory University School of Medicine, Emory University, 1364 Clifton Road NE, Atlanta, GA, 30322, USA. gdantes@emory.edu.
Olivia KeaneDepartment of Surgery, Emory University School of Medicine, Emory University, 1364 Clifton Road NE, Atlanta, GA, 30322, USA.
Isabella AmanieraEmory University School of Medicine, Emory University, Atlanta, GA, USA.
Morgan BuchananEmory University School of Medicine, Emory University, Atlanta, GA, USA.
Zhulin HePediatric Biostatistics Core, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.
Hanna AlemayehuDivision of Pediatric Surgery, Department of Surgery, School of Medicine, Emory University, Children's Healthcare of Atlanta, Atlanta, GA, USA.
Amina M BhatiaDivision of Pediatric Surgery, Department of Surgery, School of Medicine, Emory University, Children's Healthcare of Atlanta, Atlanta, GA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSpontaneous intestinal perforation (SIP) is a morbid condition of low-birth-weight neonates. Peritoneal drainage (PD), as opposed to upfront laparotomy (LP), is favored for SIP. However, PD management is neither standardized nor thoroughly understood. We reviewed our experience of PD in infants with SIP.

methodsNeonates treated for SIP between 07/2004 and 03/2023 were reviewed. Patients with NEC or death immediately following PD were excluded. Patients treated with a PD that required LP within 30 days were considered salvage laparotomy (SL).

resultsA total of 235 neonates were included. The median gestational age and birth weight were 25.0 weeks (IQR: 24.1, 26.3) and 720 g (IQR: 620, 865). Ninety-three (39.6%) patients required SL at a median of 9 days (IQR: 5, 14) from PD. Indications for failure included recurrent pneumoperitoneum (52%), clinical deterioration (20%), and ongoing feculent drain output (14%). At SL, 8.4% of patients were found to have NEC. SL patients had extended length of stay: 113 days (IQR: 86, 153) vs. 67 days (IQR: 38, 115), p < 0.001.

conclusionPD is an important tool in the management of SIP, however SL is not uncommon (39%) and has clinical significance. Prospective data to improve PD management is needed.

Indexed as

DrainageIntestinal PerforationFemaleHumansInfant, NewbornLaparotomyMaleRetrospective StudiesSalvage TherapyTreatment OutcomeDrainFocal Intestinal PerforationNecrotizing enterocolitisPeritoneal drainSalvage LaparotomySpontaneous Intestinal Perforation

Identifiers

PMID42168716

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.