Evidence map›Paper›PMID 42168555›Full record

ArticleScientific reports2026

The prevalence of E198A and F200Y single nucleotide polymorphism in Haemonchus contortus populations from Polish goat herds.

Zofia Nowek, Marcin Mickiewicz, Michał Czopowicz, Agata Moroz-Fik, Adrian-Valentin Potărniche, Kinga Biernacka, Tomasz Nalbert, Olga Szaluś-Jordanow, Paweł Górski, Alistair Antonopoulos and 4 more

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Zofia NowekDivision of Veterinary Epidemiology and Economics, Institute of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, 02-776, Warsaw, Poland.
Marcin MickiewiczDivision of Veterinary Epidemiology and Economics, Institute of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, 02-776, Warsaw, Poland. marcin_mickiewicz@sggw.edu.pl.
Michał CzopowiczDivision of Veterinary Epidemiology and Economics, Institute of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, 02-776, Warsaw, Poland.
Agata Moroz-FikDivision of Veterinary Epidemiology and Economics, Institute of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, 02-776, Warsaw, Poland.
Adrian-Valentin PotărnicheDepartment of Infectious Diseases and Preventive Medicine, Law and Ethics, University of Agricultural Sciences and Veterinary Medicine, 400372, Cluj-Napoca, Romania.
Kinga BiernackaDivision of Veterinary Epidemiology and Economics, Institute of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, 02-776, Warsaw, Poland.
Tomasz NalbertFaculty of Biological and Veterinary Sciences, Nicolaus Copernicus University, Lwowska 1, 87-100, Toruń, Poland.
Olga Szaluś-JordanowDepartment of Small Animal Diseases with Clinic, Institute of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, 02-776, Warsaw, Poland.
Paweł GórskiDivision of Parasitology and Invasiology, Department of Preclinical Sciences, Institute of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, 02-786, Warsaw, Poland.
Alistair AntonopoulosKreavet, 9150, Kruibeke, Belgium.
Iwona Markowska-DanielDivision of Veterinary Epidemiology and Economics, Institute of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, 02-776, Warsaw, Poland.
Emilia BagnickaInstitute of Genetics and Animal Biotechnology, Polish Academy of Sciences, Postępu 36A, Jastrzębiec, 02-552, Magdalenka, Poland.
Marián VáradyInstitute of Parasitology, Slovak Academy of Sciences, 04001, Košice, Slovakia.
Jarosław KabaDivision of Veterinary Epidemiology and Economics, Institute of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, 02-776, Warsaw, Poland.

Funding

Narodowe Centrum Nauki DEC-2020/37/B/NZ6/00457
6 · The paper itself

Abstract

A cross-sectional descriptive study was carried out on a study population of 81 goat herds to investigate the prevalence and frequency of two single nucleotide polymorphisms (SNPs; E198A and F200Y) associated with resistance to benzimidazoles (BZ) in Haemonchus contortus populations of goats in Poland. The distribution of gastrointestinal nematode (GIN) genera/species in a pooled fecal sample from each herd was determined in larval cultures and the presence of H. contortus DNA in larval cultures was confirmed using real-time PCR. SNPs were detected and their frequency was quantified using pyrosequencing. The Hardy-Weinberg principle was employed to estimate frequencies of H. contortus genotypes based on frequencies of alleles containing each SNP. At least one BZ resistance-associated SNP was detected in each within-herd (WH) H. contortus population-F200Y SNP in 79/81 WH H. contortus populations (98%) and E198A SNP in 80/81 WH H. contortus populations (99%). The median WH frequencies of F200Y and E198A were 86% and 8%, respectively. In the total Polish H. contortus population, the overall frequency of BZ-resistant genotypes was estimated at 89% (CI 95%: 82%-93%) and was positively and independently associated with the purchase of goats abroad (adjusted odds ratio [OR

Indexed as

Goat DiseasesGoatsHaemonchiasisHaemonchusPolymorphism, Single NucleotideAnimalsBenzimidazolesCross-Sectional StudiesDrug ResistanceFemaleGenotypePolandPrevalenceBenzimidazolesAnthelmintic resistanceBenzimidazoleGINGoatsSNP

Identifiers

PMID42168555
PMCPMC13402587

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.