Evidence map›Paper›PMID 42168467›Full record

ArticleScientific reports2026

Lack of association between ADRB2 (Gln27Glu) variant with susceptibility, severity and salbutamol response in South Indian asthmatics.

Srinivas Bandaru, Sudha Bodduluri, Radhika Swami, Rinku Chaudhary, Khushboo Sharma, Arshiya Khan, Someswar Rao Sagurthi, Koteswara Reddy Gujjula, Praveen Kumar Vemuri, Anuraj Nayarisseri

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Srinivas BandaruDepartment of Biotechnology, Koneru Lakshmiah Educational Foundation (KLEF), Green Fields, Vaddeswaram, 522302, Andhra Pradesh, India.
Sudha BodduluriDepartment of Biotechnology, Koneru Lakshmiah Educational Foundation (KLEF), Green Fields, Vaddeswaram, 522302, Andhra Pradesh, India.
Radhika SwamiIn silico Research Laboratory, Eminent Biosciences, 91, Sector-A, Mahalakshmi Nagar, Indore, 452010, Madhya Pradesh, India.
Rinku ChaudharyIn silico Research Laboratory, Eminent Biosciences, 91, Sector-A, Mahalakshmi Nagar, Indore, 452010, Madhya Pradesh, India.
Khushboo SharmaIn silico Research Laboratory, Eminent Biosciences, 91, Sector-A, Mahalakshmi Nagar, Indore, 452010, Madhya Pradesh, India.
Arshiya KhanIn silico Research Laboratory, Eminent Biosciences, 91, Sector-A, Mahalakshmi Nagar, Indore, 452010, Madhya Pradesh, India.
Someswar Rao SagurthiSpecial Center for Molecular Medicine, Jawaharlal Nehru University, New Delhi, 110067, India.
Koteswara Reddy GujjulaDepartment of Biotechnology, Koneru Lakshmiah Educational Foundation (KLEF), Green Fields, Vaddeswaram, 522302, Andhra Pradesh, India.
Praveen Kumar VemuriDepartment of Biotechnology, Koneru Lakshmiah Educational Foundation (KLEF), Green Fields, Vaddeswaram, 522302, Andhra Pradesh, India.
Anuraj NayarisseriIn silico Research Laboratory, Eminent Biosciences, 91, Sector-A, Mahalakshmi Nagar, Indore, 452010, Madhya Pradesh, India. anuraj@eminentbio.com.ORCID https://orcid.org/0000-0003-2567-9630

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ADRB2 gene polymorphisms have been widely studied for their role in influencing asthma pathophysiology. Of particular note, the Gln27Glu (+ 79 C > G, rs1042714) polymorphism, which alters the extracellular domain at the N-terminus of β

Indexed as

AlbuterolAsthmaGenetic Predisposition to DiseasePolymorphism, Single NucleotideReceptors, Adrenergic, beta-2Adrenergic beta-2 Receptor AgonistsAdultAllelesCase-Control StudiesFemaleGenotypeHumansIndiaMaleMiddle AgedRespiratory Function TestsADRB2 protein, humanAdrenergic beta-2 Receptor AgonistsAlbuterolReceptors, Adrenergic, beta-2Bronchial AsthmaBronchodilator responseDisease susceptibilityGln27Glu polymorphismLung functionSeverity

Identifiers

PMID42168467
PMCPMC13396444

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.